Journal of Pediatric Neurology - Volume 5, issue 4

Authors: Hussain, Nahin | Chieng, Siik Kwong | Rickett, Andrew | Gosalakkal, Jayprakash

Article Type: Research Article

Abstract: Cerebral sinovenous thrombosis (CSVT) is a rare and under-diagnosed complication of childhood nephrotic syndrome. With the advent of magnetic resonance imaging and magnetic resonance venography scans, CSVT cases are now being diagnosed more frequently. We report case of a three-year-old male child, known case of steroid responsive nephrotic syndrome, who presented with a 3-week history of headache and sudden onset intermittent convergent squint. He was diagnosed to have CSVT on magnetic resonance imaging and magnetic resonance …venography of the brain. Devastating cerebral infarction was probably prevented with early institution of low molecular weight heparin. Nevertheless, randomized placebo-controlled studies are necessary for assessing its efficacy and absence of risk in children. Show more

Keywords: Venous thrombosis, cerebral, nephrotic syndrome

Citation: Journal of Pediatric Neurology, vol. 5, no. 4, pp. 327-330, 2007

Authors: Yilmaz, Kutluhan | Yilmaz, Mustafa | Sirikci, Akif

Article Type: Research Article

Abstract: Positron emission tomography (PET), as a functional neuroimaging technique, provides biochemical and molecular information about brain and tumor tissues. We present the findings of FDG (2-deoxy-2[18F]-fluoro-D-glucose)-PET and magnetic resonance imaging in a 7-year-girl with tuberous sclerosis. Cranial magnetic resonance imaging revealed multiple cortical tubers, subependymal nodules and a subependymal giant cell astrocytoma. On FDG-PET images, the regions of cortical tubers were hypometabolic and the tumor also demonstrated hypometabolism implying a low-grade tumor. …PET has been studied in tuberous sclerosis for many purposes including epilepsy and mental retardation. The present report suggests that FDG-PET could be useful in patients with tuberous sclerosis and intraventricular tumor as well. Show more

Keywords: Tuberous sclerosis, positron emission tomography

Citation: Journal of Pediatric Neurology, vol. 5, no. 4, pp. 331-334, 2007

Authors: Kolthof, Henk Jan | Tjeenk-Kalff, Ariane C.

Article Type: Research Article

Abstract: Cerebral disorders are nowadays seen as a feature of nephropathic cystinosis. Describing specific cognitive profiles in children with cystinosis may help to elucidate the cause of the impairments seen. A 9-year-old girl with nephropathic cystinosis had a progressive decline in mental functioning, in particular severe memory problems. None of the cases reviewed described memory problems at such a young age, so it is difficult to ascertain the possible cause of the impairment. Although few cases with …dementia are reported, there is apparently no direct association between cystinosis and memory problems. Neither has the medication cysteamine been associated with memory loss in humans. Show more

Keywords: Cystinosis, memory problems, complications

Citation: Journal of Pediatric Neurology, vol. 5, no. 4, pp. 335-341, 2007

Authors: Arantes, Mavilde | Perdigao, Sandra | Pereira, Jorge Resende | Costa, Manuela

Article Type: Research Article

Abstract: Schizencephaly is an uncommon disorder of cell migration characterized by communication clefts between ventricular system and subarachnoid space. The clefts may be unilateral or bilateral and may be closed or separated. Patients with bilateral clefts typically present with severe mental deficits, motor anomalies and seizures. We report a 16-year-old girl whose cranial magnetic resonance imaging revealed bilateral open-lip schizencephaly, but with an atypical clinical course. She had minimally recognizable neurological deficits and …epilepsy for last one year. Such mild clinical phenotypes were not proportional to the magnetic resonance imaging of the cerebral malformation. Show more

Keywords: Migration disorder, schizencephaly, magnetic resonance image

Citation: Journal of Pediatric Neurology, vol. 5, no. 4, pp. 343-345, 2007

Authors: Singhi, Pratibha | Mahajan, Vikas

Article Type: Research Article

Abstract: Paroxysmal dyskinesias are neurologic conditions characterized by sudden episodes of abnormal involuntary movements. Paroxysmal exertion induced dyskinesia is a rare condition characterized by abnormal involuntary movements on exercise, which get relieved with rest. In general, these movements are poorly responsive to medical treatment. We report one family in which all three male members are affected and had good response to phenytoin.

Keywords: Dyskinesia, paroxysmal, exercise, phenytoin

Citation: Journal of Pediatric Neurology, vol. 5, no. 4, pp. 347-350, 2007

Authors: Wani, Abrar Ahad | Babu, Makhan Lal | Kirmani, Altaf | Ramzan, Altaf Umer | Bhat, Abdul Rashid | Alam, Syed Shafiq | Ahmad, Altaf | Baba, Khalil Mohammad

Article Type: Research Article

Abstract: Giant cell tumor of the bone accounts for 4–5% of all primary bone tumors. Spine is the fourth common site for their occurrence and axis is a relatively rare site. A case of giant cell tumor of axis in a 17-year-old male is hereby reported. The patient underwent transoral decompression and posterior fusion. Postoperatively patient had no neurological deficit and biopsy revealed the tumor as giant cell tumor.

Keywords: Giant cell tumor, axis

Citation: Journal of Pediatric Neurology, vol. 5, no. 4, pp. 351-354, 2007

Authors: Yoshikawa, Hideto

Article Type: Other

Citation: Journal of Pediatric Neurology, vol. 5, no. 4, pp. 355-356, 2007

Authors: Kumar, Raj | Das, Nitu Kumar | Mahapatra, Ashok Kumar

Article Type: Other

Citation: Journal of Pediatric Neurology, vol. 5, no. 4, pp. 357-359, 2007