Journal of Pediatric Neurology - Volume 5, issue 2
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Journal of Pediatric Neurology is an English multidisciplinary peer-reviewed medical journal publishing articles in the fields of child neurology, pediatric neurosurgery, pediatric neuroradiology, child psychiatry and pediatric neuroscience.
Journal of Pediatric Neurology encourages submissions from authors throughout the world. The following articles will be considered for publication: editorials, original and review articles, rapid communications, case reports, letters to the editor and book reviews. The aim of the journal is to share and disseminate knowledge between all disciplines that work in the field of pediatric neurology.
Abstract: We have been prescribing low dose oral penicillin to an 8-year-old boy with pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections. Neither symptom exacerbation nor increase in antistreptolysin O titer was observed after this prophylaxis. The significance of penicillin prophylaxis for the control of pediatric autoimmune neuropsychiatric disorder associated with streptococcal infection exacerbation is discussed in light of the current literature.
Abstract: A case of childhood chronic inflammatory demyelinating polyneuropathy (CIDP) due to Epstein-Barr virus (EBV) infection is reported. A 15-year-old male presented with CIDP, which initially mimicked Guillain-Barré syndrome. He subsequently developed major relapses at four and five months after initial presentation. He recovered six weeks after the last relapse. Serological studies showed positive Epstein-Barr nuclear antigen IgG and negative EBV viral capsid antigen IgM. However, EBV deoxyribonucleic acid was detected by polymerase…chain reaction from cerebrospinal fluid, measuring up to 1000 copies/mL. His CIDP, which ran a relapsing course, could be explained by reactivation of latent EBV, triggered by other viral illness. Given patient's full recovery, the mechanism of injury is likely due to EBV-associated immune-mediated process, rather than from a direct viral infiltration of the peripheral nerve. This is the first report of a CIDP with documented EBV infection in cerebrospinal fluid.
Abstract: Cavernous sinus tuberculoma is very rare. This is the first reported case in a child. A 3-year-old girl presented with progressive cavernous syndrome even though adequate antibiotics had been given. Neuroimaging could not conclusively differentiate other previously reported cavernous lesions such as lymphoma, meningioma, or fungal infection. A cavernous biopsy was not allowed by her parents, but antituberculous agents were given due to abnormal chest film, reactive tuberculin test, and positive Mycobacterium…tuberculosis culture from the gastric contents. Complete recovery occurred without other medication. Cavernous tuberculoma was inferred from the therapeutic response to antituberculous agents.
Abstract: A case of immunoassay proven West Nile virus encephalitis in a six-year old girl with a ventriculoperitoneal shunt is described. The patient was initially evaluated for shunt dysfunction, but further testing revealed viral encephalitis. Importantly, once the diagnosis was confirmed, the child's treatment and recovery did not require shunt revision. This is the first reported case of the diagnosis and treatment of West Nile virus encephalitis in the setting of ventriculoperitoneal shunting.
Keywords: West Nile virus, hydrocephalus, encephalitis, ventriculoperitoneal shunt
Abstract: There are very few reports of meningoencephalitis and myositis subsequent to hepatitis A virus (HAV). This case study reports a patient with serologically proven HAV infection, associated with meningoencephalitis and myositis. Since HAV infection might pass unnoticed, as many cases remain anicteric or subclinical, HAV should be considered as one of the etiological agents in meningoencephalitis.
Keywords: Hepatitis A, meningoencephalitis, myositis
Abstract: A 3-year-male child was operated for 4th ventricular choroid plexus carcinoma. He presented with features of raised intracranial pressure and midline posterior fossa syndrome. A total excision of tumor could be achieved as there was no parenchymal invasion or adherence with the walls of 4th ventricle. Cerebrospinal fluid pathway was reestablished and hydrocephalus resolved gradually. The child developed peritoneal and liver metastases at follow-up of 14-month without local recurrence. A choroid plexus carcinoma…metastasizes to the liver and peritoneum.
Abstract: Botulism is caused by the toxin produced by Clostridium botulinum. This toxin binds the peripheral presynaptic cholinergic membranes, preventing the release of acetylcholine and thereby producing a life-threatening, paralytic illness. We report the case of an infant with botulism who proceeded to cardiorespiratory arrest, but whose outcome was very satisfactory, in spite of the delay in diagnosis.