Low dose oral penicillin prophylaxis to PANDAS

Article type: Research Article

Authors: Kuramochi, Yukio^; | Koizumi, Shinya^; | Morita, Toshisada | Watanabe, Masanori | Hashimoto, Kiyoshi

Affiliations: Department of Pediatrics, Shizuoka Medical Center, Shizuoka, Japan | Department of Pediatrics, Nippon Medical School, Tokyo, Japan | Watanabe Clinic, Shizuoka, Japan

Note: [] Correspondence: Yukio Kuramochi, M.D., Department of Pediatrics, Shizuoka Medical Center, 762-1 Nagasawa, Shimizu-cho, Sunto-gun, Shizuoka 411-8611, Japan. Tel.: +81 55 975 2000; Fax: +81 55 975 2725; E-mail: [email protected]

Abstract: We have been prescribing low dose oral penicillin to an 8-year-old boy with pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections. Neither symptom exacerbation nor increase in antistreptolysin O titer was observed after this prophylaxis. The significance of penicillin prophylaxis for the control of pediatric autoimmune neuropsychiatric disorder associated with streptococcal infection exacerbation is discussed in light of the current literature.

Keywords: Pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections, penicillin prophylaxis

Journal: Journal of Pediatric Neurology, vol. 5, no. 2, pp. 149-151, 2007