Journal of Pediatric Neurology - Volume 10, issue 4

Authors: Thabet, Farouq I. | Bozarth, Xiuhua L. | Barboi, Alexandru C.

Article Type: Research Article

Abstract: A 16-year-old patient presented with three presyncopal episodes, muscle weakness, elevated creatine kinase and myopathic changes on electromyography, was diagnosed with Addison's disease through laboratory testing. Corticosteroid replacement produced marked improvement in muscle strength and normalized creatine kinase levels. In children, low corticosteroid state should be considered in the differential diagnosis of a myopathy, particularly in the setting of other signs and symptoms of adrenal insufficiency. To our knowledge, this is the …first case report of a myopathy as the initial presentation of Addison's disease in this age group. Show more

Keywords: Myopathy, elevated creatine kinase, Addison's disease

DOI: 10.3233/JPN-120580

Citation: Journal of Pediatric Neurology, vol. 10, no. 4, pp. 309-312, 2012

Authors: Chamdine, Omar M. | Shatila, Abdul-Rahman S. | Yassin, Nabil A. | Muwakkit, Samar A. | Ibrahim, Ahmad O.

Article Type: Research Article

Abstract: Posterior reversible encephalopathy syndrome (PRES) is a recently described clinic-radiological entity. It has been associated with a number of medical conditions, such as eclampsia, arterial hypertension, renal failure, and vasculitis. Drugs causing immunosuppression such as cyclosporine A, tacrolimus, cancer chemotherapy, and steroids have been implicated in the etiology of PRES. Its pathogenesis remains poorly understood. Clinical findings are not sufficiently specific; however, neuroimaging is often characteristic. Few cases of PRES were reported …in children who were treated for cancer, most of whom had acute lymphoblastic leukemia. This case-report describes PRES following allogeneic bone marrow transplantation in a child with acute lymphocytic leukemia. Show more

Keywords: PRES, cyclosporine, BMT

DOI: 10.3233/JPN-120573

Citation: Journal of Pediatric Neurology, vol. 10, no. 4, pp. 313-316, 2012

Authors: Vargiami, Euthymia | Bounta, Adriana | Pardalos, Grigoris | Gombakis, Nikos | Zafeiriou, Dimitrios

Article Type: Research Article

DOI: 10.3233/JPN-120571

Citation: Journal of Pediatric Neurology, vol. 10, no. 4, pp. 317-318, 2012

Article Type: Correction

DOI: 10.3233/JPN-120570

Citation: Journal of Pediatric Neurology, vol. 10, no. 4, pp. 319-319, 2012

Article Type: Other

Citation: Journal of Pediatric Neurology, vol. 10, no. 4, pp. 321-325, 2012

Article Type: Other

Citation: Journal of Pediatric Neurology, vol. 10, no. 4, pp. 327-329, 2012