Journal of Pediatric Neurology - Volume 10, issue 4
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Journal of Pediatric Neurology is an English multidisciplinary peer-reviewed medical journal publishing articles in the fields of child neurology, pediatric neurosurgery, pediatric neuroradiology, child psychiatry and pediatric neuroscience.
Journal of Pediatric Neurology encourages submissions from authors throughout the world. The following articles will be considered for publication: editorials, original and review articles, rapid communications, case reports, letters to the editor and book reviews. The aim of the journal is to share and disseminate knowledge between all disciplines that work in the field of pediatric neurology.
Abstract: A 16-year-old patient presented with three presyncopal episodes, muscle weakness, elevated creatine kinase and myopathic changes on electromyography, was diagnosed with Addison's disease through laboratory testing. Corticosteroid replacement produced marked improvement in muscle strength and normalized creatine kinase levels. In children, low corticosteroid state should be considered in the differential diagnosis of a myopathy, particularly in the setting of other signs and symptoms of adrenal insufficiency. To our knowledge, this is the…first case report of a myopathy as the initial presentation of Addison's disease in this age group.
Abstract: Posterior reversible encephalopathy syndrome (PRES) is a recently described clinic-radiological entity. It has been associated with a number of medical conditions, such as eclampsia, arterial hypertension, renal failure, and vasculitis. Drugs causing immunosuppression such as cyclosporine A, tacrolimus, cancer chemotherapy, and steroids have been implicated in the etiology of PRES. Its pathogenesis remains poorly understood. Clinical findings are not sufficiently specific; however, neuroimaging is often characteristic. Few cases of PRES were reported…in children who were treated for cancer, most of whom had acute lymphoblastic leukemia. This case-report describes PRES following allogeneic bone marrow transplantation in a child with acute lymphocytic leukemia.