Affiliations: Department of Neurology, Pediatric Neurology Division,
Medical College of Wisconsin, Milwaukee, WI, USA | Department of Neurology, Medical College of Wisconsin,
Milwaukee, WI, USA
Note: [] Correspondence: Farouq I. Thabet, MD, Department of Neurology,
Pediatric Neurology Fellow, Division of Pediatric Neurology, Medical College of
Wisconsin, Children's Hospital of Wisconsin, 9000 West Wisconsin Avenue, CHW
CCC, Suite C540, Milwaukee, WI 53226, USA. Tel.: +1 414 266 7540; Fax: +1 414
337 7908; E-mail: [email protected]
Abstract: A 16-year-old patient presented with three presyncopal episodes,
muscle weakness, elevated creatine kinase and myopathic changes on
electromyography, was diagnosed with Addison's disease through laboratory
testing. Corticosteroid replacement produced marked improvement in muscle
strength and normalized creatine kinase levels. In children, low corticosteroid
state should be considered in the differential diagnosis of a myopathy,
particularly in the setting of other signs and symptoms of adrenal
insufficiency. To our knowledge, this is the first case report of a myopathy as
the initial presentation of Addison's disease in this age group.
