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Biorheology is an international interdisciplinary journal that publishes research on the deformation and flow properties of biological systems or materials. It is the aim of the editors and publishers of
Biorheology to bring together contributions from those working in various fields of biorheological research from all over the world. A diverse editorial board with broad international representation provides guidance and expertise in wide-ranging applications of rheological methods to biological systems and materials.
The aim of biorheological research is to determine and characterize the dynamics of physiological processes at all levels of organization. Manuscripts should report original theoretical and/or experimental research promoting the scientific and technological advances in a broad field that ranges from the rheology of macromolecules and macromolecular arrays to cell, tissue and organ rheology. In all these areas, the interrelationships of rheological properties of the systems or materials investigated and their structural and functional aspects are stressed.
The scope of papers solicited by
Biorheology extends to systems at different levels of organization that have never been studied before, or, if studied previously, have either never been analyzed in terms of their rheological properties or have not been studied from the point of view of the rheological matching between their structural and functional properties. This biorheological approach applies in particular to molecular studies where changes of physical properties and conformation are investigated without reference to how the process actually takes place, how the forces generated are matched to the properties of the structures and environment concerned, proper time scales, or what structures or strength of structures are required.
Biorheology invites papers in which such 'molecular biorheological' aspects, whether in animal or plant systems, are examined and discussed. While we emphasize the biorheology of physiological function in organs and systems, the biorheology of disease is of equal interest. Biorheological analyses of pathological processes and their clinical implications are encouraged, including basic clinical research on hemodynamics and hemorheology.
In keeping with the rapidly developing fields of mechanobiology and regenerative medicine,
Biorheology aims to include studies of the rheological aspects of these fields by focusing on the dynamics of mechanical stress formation and the response of biological materials at the molecular and cellular level resulting from fluid-solid interactions. With increasing focus on new applications of nanotechnology to biological systems, rheological studies of the behavior of biological materials in therapeutic or diagnostic medical devices operating at the micro and nano scales are most welcome.
Abstract: Measurements, employing the Weissenberg rheogoniometer, were made of the rigidity modulus of fibrin gels in unidirectional shear. The system of purified preparations of fibrinogen and thrombin was free of transamidase and the fibrin gel was soluble in urea or lithium bromide. Two significant changes were observed in the slope of semilog plot of the rigidity modulus versus time within the first sixty minutes of the conversion of fibrinogen to fibrin. These changes in the slopes are discussed in relation to the roles of fibrinopeptides A and B, as well as other factors which may contribute to the gel structure.
Abstract: The flow of ACD-treated human blood through hollow precision drawn glass fibers 40 to 70μ in lumen has been observed with high speed microcinematography, both under steady and pulsating conditions (the latter at values of the pulsatile Reynolds number a less than 0.36). Analysis of the data included velocity distributions of the erythrocytes (for pulsating flow at several points in a pressure cycle), peripheral layer characteristics, pressure losses and erythrocyte rotation rates. In pulsating flow, the velocity distributions were in phase with the pressure gradient, and the peripheral layer dimensions were not noticeably different from those…for steady flow, providing a microscopic confirmation of the negligible effect, in smaller vessels, of inertial effects due to the pulsating nature of the flow. The velocity distributions for both steady and pulsating conditions fell generally between those described by models which assume the erythrocytes to be either uniformly distributed in the cross section, or concentrated in a central region of uniform radius.
Abstract: A general formula has been derived rigorously for the circumferential tension in a hollow cylindrical tube in equilibrium under constant internal and external pressure. The relationship between our formula and the law of Laplace is discussed. It is shown that the circumferential tension may take positive or negative value, depending upon the pressure and the radius of the tube. The stress distribution in a tube wall with Hookean elasticity is discussed in detail with special reference to s k -plane, where s is the radius ratio and k is the pressure ratio.
vol. 7, no. 2, pp. 109-117, 1970
Abstract: The mechanical properties of collagen fibres obtained from mammalian, avian, reptilian and other sources were determined under identical conditions of testing. The results showed wide variations in the mean breaking length and extension at break of the different samples tested. It is unlikely that the differences in the amino acid composition are responsible for this variation which may probably be due to the differences in the nature and extent of non-collagenous components associated with the protein. There was a correlation between the fibrillar width and the fibre strength in collagen.
vol. 7, no. 2, pp. 119-124, 1970
Abstract: An equation is derived which describes the rate of flow: pressure characteristic of blood flowing through a rigid tube. The method adopted combines the concepts of a marginal zone of plasma and of a coherence resistance within the central core of plasma and cells. The equation thus derived IS in good agreement with experimental data, and provides an estimate of the coherence resistance.
vol. 7, no. 2, pp. 125-128, 1970
Abstract: The various methods advocated for the measurement of the yield-stress for human blood are reviewed. In order to be clearer, a distinction is made between the static methods and the dynamic methods. A comparison between the different methods shows a great disparity in the results, the interpretation of which remains questionable.
vol. 7, no. 2, pp. 129-135, 1970