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Biorheology is an international interdisciplinary journal that publishes research on the deformation and flow properties of biological systems or materials. It is the aim of the editors and publishers of
Biorheology to bring together contributions from those working in various fields of biorheological research from all over the world. A diverse editorial board with broad international representation provides guidance and expertise in wide-ranging applications of rheological methods to biological systems and materials.
The aim of biorheological research is to determine and characterize the dynamics of physiological processes at all levels of organization. Manuscripts should report original theoretical and/or experimental research promoting the scientific and technological advances in a broad field that ranges from the rheology of macromolecules and macromolecular arrays to cell, tissue and organ rheology. In all these areas, the interrelationships of rheological properties of the systems or materials investigated and their structural and functional aspects are stressed.
The scope of papers solicited by
Biorheology extends to systems at different levels of organization that have never been studied before, or, if studied previously, have either never been analyzed in terms of their rheological properties or have not been studied from the point of view of the rheological matching between their structural and functional properties. This biorheological approach applies in particular to molecular studies where changes of physical properties and conformation are investigated without reference to how the process actually takes place, how the forces generated are matched to the properties of the structures and environment concerned, proper time scales, or what structures or strength of structures are required.
Biorheology invites papers in which such 'molecular biorheological' aspects, whether in animal or plant systems, are examined and discussed. While we emphasize the biorheology of physiological function in organs and systems, the biorheology of disease is of equal interest. Biorheological analyses of pathological processes and their clinical implications are encouraged, including basic clinical research on hemodynamics and hemorheology.
In keeping with the rapidly developing fields of mechanobiology and regenerative medicine,
Biorheology aims to include studies of the rheological aspects of these fields by focusing on the dynamics of mechanical stress formation and the response of biological materials at the molecular and cellular level resulting from fluid-solid interactions. With increasing focus on new applications of nanotechnology to biological systems, rheological studies of the behavior of biological materials in therapeutic or diagnostic medical devices operating at the micro and nano scales are most welcome.
Abstract: A theoretical study of a sphere moving with a constant velocity along a deformable tube filled with a homogenous incompressible viscous fluid is presented. An axi-symmetrical shell model is used in our formulation. Approximate expressions of pressure and drag on the sphere are derived for the “hard tube” case. The bending effect cannot be neglected when the deflection of the tube wall is comparable to the film thickness. The drag on the sphere is decreased due to the deformable wall.
vol. 6, no. 4, pp. 307-314, 1970
Abstract: Foetal blood was studied in a cone-in-cone viscometer. Calibration of the instrument required consideration of Reynold’s number at high rev./min. In vitro adjustments were made to determine the separate effects of red cell concentration, plasma viscosity, pH and osmolality on the viscosity of blood. Procedures designed to change pH also altered plasma osmolality. Hyper- and hypotonicity of plasma both increased blood viscosity. Fall in pH increased blood viscosity. The part which change in osmolality played in this was calculable. The mechanism of the increase in viscosity with fall in pH could not be certainly…deduced. It was, however, greater by a factor of 50 per cent or more, depending on the shear rate at which tested, than that accountable by the swelling of cells from fall in pH. It is therefore suggested that an important factor in the elevated viscosity of blood at low pH is an increased rigidity of the erythrocyte from an effect of H+ on the cell membrane or contents.
vol. 6, no. 4, pp. 315-328, 1970
Abstract: Marked nonlinearity between stress and strain was observed during the clotting of plasma and blood. Dynamic elastic modulus and loss modulus of plasma clot decreased with the frequency and amplitude of oscillation given to the plasma during clotting. The breaking amplitude for the clot was higher if the larger amplitude of oscillation was used during clotting. When the measuring amplitude was small, the elastic modulus increased with the rise of temperature. On the other hand, when the measuring amplitude was large, the modulus decreased with the rise of temperature. These results can be explained by assuming that the fibrin…strands between crosslinks in the network are in a fairly elongated state. When the plasma was clotted under a sinusoidal shear strain of about 0.08, the number of fibrin monomers between crosslinks was estimated to be about 20.
vol. 6, no. 4, pp. 329-339, 1970