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Biorheology is an international interdisciplinary journal that publishes research on the deformation and flow properties of biological systems or materials. It is the aim of the editors and publishers of
Biorheology to bring together contributions from those working in various fields of biorheological research from all over the world. A diverse editorial board with broad international representation provides guidance and expertise in wide-ranging applications of rheological methods to biological systems and materials.
The aim of biorheological research is to determine and characterize the dynamics of physiological processes at all levels of organization. Manuscripts should report original theoretical and/or experimental research promoting the scientific and technological advances in a broad field that ranges from the rheology of macromolecules and macromolecular arrays to cell, tissue and organ rheology. In all these areas, the interrelationships of rheological properties of the systems or materials investigated and their structural and functional aspects are stressed.
The scope of papers solicited by
Biorheology extends to systems at different levels of organization that have never been studied before, or, if studied previously, have either never been analyzed in terms of their rheological properties or have not been studied from the point of view of the rheological matching between their structural and functional properties. This biorheological approach applies in particular to molecular studies where changes of physical properties and conformation are investigated without reference to how the process actually takes place, how the forces generated are matched to the properties of the structures and environment concerned, proper time scales, or what structures or strength of structures are required.
Biorheology invites papers in which such 'molecular biorheological' aspects, whether in animal or plant systems, are examined and discussed. While we emphasize the biorheology of physiological function in organs and systems, the biorheology of disease is of equal interest. Biorheological analyses of pathological processes and their clinical implications are encouraged, including basic clinical research on hemodynamics and hemorheology.
In keeping with the rapidly developing fields of mechanobiology and regenerative medicine,
Biorheology aims to include studies of the rheological aspects of these fields by focusing on the dynamics of mechanical stress formation and the response of biological materials at the molecular and cellular level resulting from fluid-solid interactions. With increasing focus on new applications of nanotechnology to biological systems, rheological studies of the behavior of biological materials in therapeutic or diagnostic medical devices operating at the micro and nano scales are most welcome.
Abstract: A cone and plate viscometer, the Weissenberg rheogoniometer, is used to study the viscosity of synovial fluid from the radiocarpal joint of cattle. A sinusoidal movement of low amplitude is applied to the lower conical platen and the movements of both platens are recorded. The movement detected at the upper platen is shown to increase markedly about the natural frequency of the torsion head, and there is also a change in the phase difference between the movements of the two platens. The viscosity of the fluid is calculated and shown to decrease as the frequency of the oscillation is…increased; there is a discontinuity of the plot on either side of the natural frequency, which persists even after the application of correction factors. The results are also difficult to interpret at the highest frequencies. A comparison is made with results obtained by rotational testing, and they are seen to correspond closely. At the lowest frequencies the fluid behaves in in a non-Newtonian fashion.
vol. 5, no. 3, pp. 189-198, 1968
Abstract: In a number of biological substances, mechanical strain and electrical polarization are closely linked together by piezoelectric effect, which is usually assigned to the property of crystals. Stress induced polarization and field induced strain were investigated in wood (cellulose), bone and tendon (collagen). The matrix of piezoelectric moduli was determined. Recently, the effect was also confirmed in soft tissues such as blood vessels, intestines, and trachea. Physiological meaning of the piezoelectric effect in biopolymers was noticed in connection with growth mechanism of bone and with the tactual sense. The study in synthetic polypeptides suggested some molecular interpretation of the effect.
vol. 5, no. 3, pp. 199-208, 1968
Abstract: Sodium oleate, representing substances that disrupt erythrocyte aggregates, has been found to considerably decrease the low shear viscosity of blood in optimal concentrations of 20–40 mg per cent. Evidence suggests that this effect is due to reversible morphological changes in the erythrocytes which facilitate disaggregation of erythrocyte aggregates. High and physiologically unbearable concentrations of 60 mg per cent and above cause an increase in the viscosity, apparently through crenation and stiffening of the red cells.
vol. 5, no. 3, pp. 209-214, 1968
Abstract: The phenomenon of stress relaxation in animal fibres, such as wool, is analysed with reference to proposed structural models for keratin. Rate of stress relaxation in wool is analysed by treating stress relaxation as a unimolecular reaction process. In general, the data fit this system reasonably well. Rate constants are given for the two samples under test. The variation in rate constants between the two samples is discussed in terms of the biological aspects of sulphur content. It is evident that the solution of problems which can be studied by special techniques applicable only to textile protein fibres…can throw considerable light on problems of structure and rheology of enzymes, viruses, hormones, and muscles. The different types of inter and intra molecular bonds can be recognized and the relationship to mechanical, physical, chemical and even physiological behaviour interpreted.
vol. 5, no. 3, pp. 215-225, 1968
Abstract: Considérant la théorie des suspensions colloïdales et la nature des forces d’attraction ct de répulsion interglobulaires, le potentiel zeta des éléments figurés est susceptible d’intervenir dans la stabilité du sang. La mobilité électrophorétique plaquettaire est influencée par l’ADP, l’ATP et la Noradrenaline in vitro . Mais l’effet de ces différentes substances est diphasique pour l’ATP et l’ADP, et il existe une nette corrélation entre cette mobilité, le potentiel zeta et la dose de produit utilisée. Un essai de corrélation in vivo réalisé sur la circulation mésentérique du rat permet de reconnaître que les doses de substances proagrégantes…et désagrégantes prévues en fonction du potentiel zeta donnent bien les résultats escomptés.
vol. 5, no. 3, pp. 227-235, 1968