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Biorheology is an international interdisciplinary journal that publishes research on the deformation and flow properties of biological systems or materials. It is the aim of the editors and publishers of
Biorheology to bring together contributions from those working in various fields of biorheological research from all over the world. A diverse editorial board with broad international representation provides guidance and expertise in wide-ranging applications of rheological methods to biological systems and materials.
The aim of biorheological research is to determine and characterize the dynamics of physiological processes at all levels of organization. Manuscripts should report original theoretical and/or experimental research promoting the scientific and technological advances in a broad field that ranges from the rheology of macromolecules and macromolecular arrays to cell, tissue and organ rheology. In all these areas, the interrelationships of rheological properties of the systems or materials investigated and their structural and functional aspects are stressed.
The scope of papers solicited by
Biorheology extends to systems at different levels of organization that have never been studied before, or, if studied previously, have either never been analyzed in terms of their rheological properties or have not been studied from the point of view of the rheological matching between their structural and functional properties. This biorheological approach applies in particular to molecular studies where changes of physical properties and conformation are investigated without reference to how the process actually takes place, how the forces generated are matched to the properties of the structures and environment concerned, proper time scales, or what structures or strength of structures are required.
Biorheology invites papers in which such 'molecular biorheological' aspects, whether in animal or plant systems, are examined and discussed. While we emphasize the biorheology of physiological function in organs and systems, the biorheology of disease is of equal interest. Biorheological analyses of pathological processes and their clinical implications are encouraged, including basic clinical research on hemodynamics and hemorheology.
In keeping with the rapidly developing fields of mechanobiology and regenerative medicine,
Biorheology aims to include studies of the rheological aspects of these fields by focusing on the dynamics of mechanical stress formation and the response of biological materials at the molecular and cellular level resulting from fluid-solid interactions. With increasing focus on new applications of nanotechnology to biological systems, rheological studies of the behavior of biological materials in therapeutic or diagnostic medical devices operating at the micro and nano scales are most welcome.
Abstract: Simultaneous measurement of apparent viscosity and mean tube hematocrits have been made at various shear rates for the flow of red blood cell suspensions through glass capillaries with diameters in the range 30 to 500 microns. Two types of red blood cell (RBC) suspensions, namely normal and heated RBC suspensions, have been used in the investigation to study the effect of erythrocyte deformability. The effect of heating on the shape and size of erythrocytes was studied through scanning electron microscopy. The hematocrit of the suspensions ranged from 5 to 65 % in the large tubes whereas in the smaller tubes…it was maintained around 40 % for both the suspensions. Experimental results on the apparent viscosity and hematocrit defect for normal RBC suspensions are found to be in good agreement with the published data in literature. The decreased deformability of the heated erythrocytes resulted in an increase in the apparent viscosity as measured in all the tubes. However, the extent of this increase was observed to depend on tube diameter, the effect being more pronounced in smaller tubes. Further, the hematocrit defect in the heated RBC suspensions was found to be less than that for the normal RBC suspensions under comparable flow conditions.