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Biorheology is an international interdisciplinary journal that publishes research on the deformation and flow properties of biological systems or materials. It is the aim of the editors and publishers of
Biorheology to bring together contributions from those working in various fields of biorheological research from all over the world. A diverse editorial board with broad international representation provides guidance and expertise in wide-ranging applications of rheological methods to biological systems and materials.
The aim of biorheological research is to determine and characterize the dynamics of physiological processes at all levels of organization. Manuscripts should report original theoretical and/or experimental research promoting the scientific and technological advances in a broad field that ranges from the rheology of macromolecules and macromolecular arrays to cell, tissue and organ rheology. In all these areas, the interrelationships of rheological properties of the systems or materials investigated and their structural and functional aspects are stressed.
The scope of papers solicited by
Biorheology extends to systems at different levels of organization that have never been studied before, or, if studied previously, have either never been analyzed in terms of their rheological properties or have not been studied from the point of view of the rheological matching between their structural and functional properties. This biorheological approach applies in particular to molecular studies where changes of physical properties and conformation are investigated without reference to how the process actually takes place, how the forces generated are matched to the properties of the structures and environment concerned, proper time scales, or what structures or strength of structures are required.
Biorheology invites papers in which such 'molecular biorheological' aspects, whether in animal or plant systems, are examined and discussed. While we emphasize the biorheology of physiological function in organs and systems, the biorheology of disease is of equal interest. Biorheological analyses of pathological processes and their clinical implications are encouraged, including basic clinical research on hemodynamics and hemorheology.
In keeping with the rapidly developing fields of mechanobiology and regenerative medicine,
Biorheology aims to include studies of the rheological aspects of these fields by focusing on the dynamics of mechanical stress formation and the response of biological materials at the molecular and cellular level resulting from fluid-solid interactions. With increasing focus on new applications of nanotechnology to biological systems, rheological studies of the behavior of biological materials in therapeutic or diagnostic medical devices operating at the micro and nano scales are most welcome.
Abstract: An investigation has been made of the variation of erythrocyte flexibility within a large healthy population. It was found that the mean values of the erythrocyte flexibility of males and females were not significantly different, but the female values were more variable than the males. A small (ca . 3%) group of subjects was found to be very significantly different from the population at large. Evidence is presented to suggest that this difference is due to a membrane abnormality.
vol. 13, no. 2, pp. 101-105, 1976
Abstract: The viscoelastic properties of tracheal mucus obtained from dogs equipped with a chronic tracheal pouch preparation were found to vary significantly during periods of exposure to sulfur dioxide inhalation. A biphasic response which apparently is due to variations in the ratio of high molecular weight glycoproteins to smaller serum-like proteins was observed. The response of the pouch mucosa to inhaled sulfur dioxide indicates that a neural or circulatory mechanism is probably involved, since the pouch is never directly exposed to the gas.
vol. 13, no. 2, pp. 107-114, 1976
Abstract: The size and shape of red cells in the blood vessels of hamster cheek pouches have been studied by analysing electron micrographs of sections through the pouches. A mathematical analysis of the shapes obtained by randomly sectioning relaxed red cells led to a simple counting technique by which the size and shape of the cells could be quantitatively assessed. In the venules their mean size was: diameter 6.05 μ m, maximum thickness 2.15 μ m, minimum thickness 0.55 μ m. In the microcirculation the relaxed cells were highly deformed, probably into cups.
vol. 13, no. 2, pp. 115-125, 1976
Abstract: Nous avons utilisé un viscosimètre Rheomat 30, du type Couette, pour mesurer la viscosité de suspension de globules rouges pour de faibles valeurs de la vitesse de déformation. Nous montrons, qu’à condition de tenir compte des effets d’extrémités et de dépouiller soigneusement les résultats bruts, ce viscosimètre est tout à fait adapté à genre de recherches. Nos résultats sont comparés à ceut d’autres auteurs.
vol. 13, no. 2, pp. 127-132, 1976
Abstract: Recently Valanis and Sun, Biorheology 6 , (1969), 85 have studied the Poiseuille flow with couple stress. While obtaining velocity profiles for various values of non-dimensional couple stress parameters α ¯ and η ¯ , they somehow find that for η ¯ = 0.5 the critical value of α ¯ , for which flow velocity is identically zero, is 0.45. Our numerical computations show that the flow velocity is not identically zero for these values of α ¯…and η ¯ . Figures 4 and 7 of (Valanis, K.C. and Sun, C.T. Biorheology 6 , (1969), 85) clearly indicate that the critical value of α ¯ depends on η ¯ . In the present note, it is analytically shown that the critical value of α ¯ is zero and it is independent of η ¯ . Due to this almost all the figures of (Valanis, K.C. and Sun, C.T. Biorheology 6 , (1969), 85) will change; the corresponding correct figures are given and the conclusions are accordingly modified.
vol. 13, no. 2, pp. 133-136, 1976
Abstract: Surgical procedures developed on a series of mongrel dogs. wherehy a hot film anemometer probe was inserted in the left renal artery nearly flush with the wall of the descending aorta, have allowed measurements of aortic wall flow disturbance distal to an artificially created partial occlusion. Results show that the presence of a soluble drag reducing polymer (Separan AP-30) in the blood causes an increase in disturbance periodicity (or decrease in frequency) averaging 60% with polymer concentrations of ca. 62 ppm. This result is in substantial agreement with current theoretical developments which predict that drag reducing flow behavior may…hinder, and in some cases prevent, the traumatic process of flow separation and reattachment. Application to current hemodynamic theories of atherogenesis suggests that reductions in local arterial wall disturbance levels may lead to a retardation in the development of atheroma.
vol. 13, no. 2, pp. 137-141, 1976
Abstract: There are several types of illness leading to changes in the viscosity of blood, plasma or serum. Determination of the viscosity alone, therefore, will not make possible an unambiguous diagnosis of any particular complaint. However, determination of the viscosity–temperature correlation in blood serum, in addition to conventional diagnostic means, can lead to more accurate diagnostic information. This is explained by the dependence of viscosity on certain physio-chemical factors.
vol. 13, no. 2, pp. 143-148, 1976