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Biorheology is an international interdisciplinary journal that publishes research on the deformation and flow properties of biological systems or materials. It is the aim of the editors and publishers of
Biorheology to bring together contributions from those working in various fields of biorheological research from all over the world. A diverse editorial board with broad international representation provides guidance and expertise in wide-ranging applications of rheological methods to biological systems and materials.
The aim of biorheological research is to determine and characterize the dynamics of physiological processes at all levels of organization. Manuscripts should report original theoretical and/or experimental research promoting the scientific and technological advances in a broad field that ranges from the rheology of macromolecules and macromolecular arrays to cell, tissue and organ rheology. In all these areas, the interrelationships of rheological properties of the systems or materials investigated and their structural and functional aspects are stressed.
The scope of papers solicited by
Biorheology extends to systems at different levels of organization that have never been studied before, or, if studied previously, have either never been analyzed in terms of their rheological properties or have not been studied from the point of view of the rheological matching between their structural and functional properties. This biorheological approach applies in particular to molecular studies where changes of physical properties and conformation are investigated without reference to how the process actually takes place, how the forces generated are matched to the properties of the structures and environment concerned, proper time scales, or what structures or strength of structures are required.
Biorheology invites papers in which such 'molecular biorheological' aspects, whether in animal or plant systems, are examined and discussed. While we emphasize the biorheology of physiological function in organs and systems, the biorheology of disease is of equal interest. Biorheological analyses of pathological processes and their clinical implications are encouraged, including basic clinical research on hemodynamics and hemorheology.
In keeping with the rapidly developing fields of mechanobiology and regenerative medicine,
Biorheology aims to include studies of the rheological aspects of these fields by focusing on the dynamics of mechanical stress formation and the response of biological materials at the molecular and cellular level resulting from fluid-solid interactions. With increasing focus on new applications of nanotechnology to biological systems, rheological studies of the behavior of biological materials in therapeutic or diagnostic medical devices operating at the micro and nano scales are most welcome.
Abstract: A mathematical model is presented for the steady flow of blood in rigid straight circular tubes. The blood is modeled as a two-layer fluid for which the constitutive equations are Newtonian for the plasma layer near the wall and Casson for the whole blood in the core. Dimensional analysis is used to obtail1 an expression for the marginal layer thickness in terms of the Reynolds and Bingham numbers and the blood hematocrit. Velocity profiles calculated from the model agree well with experimental results and the calculated marginal layer thickness has a maximum deviation of 37 per cent from experimentally determined…values. The model allows the computation of pressure drop-now rate relations from reservoir parameters of the blood and the tube diameter. and also predicts shear thinning and apparent viscosity decrease with decreasing tube diameter as observed in experiments.
vol. 11, no. 2, pp. 97-109, 1974
Abstract: The viscoelastic properties of canine tracheal secretions obtained via a chronic pouch preparation have been determined. Storage and loss shear moduli were measured both for whole unfractionated material and for fractions collected from an agarose gel column. Of the two major carbohydrate and protein containing peaks, the one eluting first and containing carbohydrate-rich glycoproteins determined essentially all the rheological behavior of the secretions. The retained peak materials containing “serum-type” glycoproteins possessed no clastic behavior.
vol. 11, no. 2, pp. 111-117, 1974
Abstract: Rheological measurements in the creep mode have been carried out on saliva and tracheobronchial mucus gels obtained from cats using a cone and plate air turbine viscometer. The results obtained show that the gel networks of these materials arc similar. Examination of the rheological and biochemical parameters of the gels showed that for mucus there was a correlation between viscosity and elasticity and protein concentration, while for saliva there was a correlation between elasticity and protein and sulphate content. No correlation could be found between the viscosity of saliva and the protein, sulphate, sialic acid or hexose content. The significance…of these results in relation to the properties of the macromolecules present in the secretions is discussed.
vol. 11, no. 2, pp. 119-128, 1974
Abstract: Rotational viscometry has been used to obtain rheograms and shear stress decay curves for bronchial mucus at 37°C and 100 per cent r.h. Statistical analysis of parameters derived from the latter curves indicated the marked variation between samples. A technique which reduces this variation whilst retaining the original rheological properties of bronchial mucus has been developed. The significance of the results with respect to biological assays is discussed.
vol. 11, no. 2, pp. 129-135, 1974