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Theory of planned behavior as a conceptual framework for the willingness to self-isolate during the COVID-19 pandemic: A regional cross-sectional study

Abstract

BACKGROUND:

Due to an unavailability of a vaccine, one of the efficient methods to prevent the spread of the novel coronavirus (COVID-19) is by applying self-isolation (SI). Hence there is an urgent need to investigate the factors leading to an individuals’ willingness to choose to self-isolate.

OBJECTIVES:

The current study utilized the Theory of Planned Behavior (TPB) as a conceptual model and aimed to investigate the extent to which subjective norms, personal attitudes and perceived control influences an individual’s willingness to self-isolate during COVID-19 risk.

METHOD:

A cross-sectional study was performed on 800 Saudi respondents aged≥18 years by using a validated self-administered questionnaire about factors related to willingness to self-isolate during COVID-19 pandemic risk based on the TPB. The effects of different variables on SI were analyzed by using ordinal logistic regression model.

RESULTS:

A total of 756 (94.5%) were completed and analyzed. Subjective norms and perceived control over the behavior significantly (p < 0.05) influenced the intention of willingness to self-isolate, while attitude was found to be insignificant. The odds of letting others to know about self COVID status were 2.40 times higher than not telling the neighbors or colleagues. A statistically significant difference (p≤0.001) existed between males and females regarding the willingness to self-isolate. Similarly the odds of willingness to self-isolate with a presence of disabled person in family were 2.88 times higher than the absence of a disability in the family. Few recommendations for the policymakers that are needed to curb the spread of COVID-19 infection are also proposed.

CONCLUSION:

The outcomes of study might be considered as an initial understanding of the factors that significantly influences an individual’s willingness to SI when facing an unprecedented pandemic risk. Additionally, these factors provide a plan for policymakers to encourage citizens for self-isolation during pandemic infections.

1Introduction

With the recent global novel coronavirus (COVID-19) outbreak, public health authorities in all affected areas scrambled to impose the preventive measures that aimed at restricting its spread. At the beginning, the health-care providers were notified about the situations and were provided with the diagnostic protocols. But very soon it was being found that the infection had spread extensively [1]. This situation has become more alarming since there are no available vaccines, drug therapies or other aggressive treatments. Eventually, preventive interventions, including quarantine of entire towns/cities, strict contact tracing, cancellation of mass events and closing of borders with travel restrictions have been implemented by majority of the countries [2]. Of all the epidemic control measures that are implemented, isolation and quarantine are perceived as most important epidemic control measures of public health interventions [1].

The Saudi authorities had imposed a complete lockdown of the nation for more than 2 months (from March 2020 until end of April 2020) but from 26th April 2020, this complete lockdown was partially lifted with few hours’ relaxation per day [3]. This incomplete lockdown indicates that henceforth the effective measure to prevent the spread of COVID-19 will be dependent on public behavior. Self-isolation (SI) is important at curtailing the spread of contagious infections and has been the focus of many studies based on different methods [4]. Unfortunately, voluntary SI strategies may be inconvenient for an individual, can cause social, psychological and economic distress or even lead to moral conflicts; thus, making it a controversial strategy [5].

Therefore, there is an urgent need to pursue the answers to the fundamental questions about what factors are associated with the willingness to self-isolate during the pandemic risk.

1.1Conceptual model

The theory of planned behavior (TPB) was undertaken as the conceptual model for the current study because it seems to fit in situations where an individual do not perceive himself as having complete control over his behavior, as might occur in individual’s intentions to self-isolate during COVID-19 pandemic [6]. This theory is one of the best-supported social psychological theories in relation to predicting human behavior and has been studied to explore a wide-range of behaviors in different populations and contexts [2, 4, 7]. The premise of TPB is that human beings make systematic use of available information and consider the consequences of their actions before engaging in a behavior [6]. With a strong intention to carry out a behavior, a person tends to perform that behavior [6]. According to the TPB (as shown in Fig. 1), behavior is influenced by the following three factors, viz [4– 6]

Fig. 1

Theoretical model of individuals’ willingness to self-isolate based on the theory of planned behavior.

Theoretical model of individuals’ willingness to self-isolate based on the theory of planned behavior.

  • 1. Attitudes toward the behavior (ATT) - reflecting an individual’s belief about a particular behavior and his evaluation of those beliefs;

  • 2. Subjective norms (SN) with respect to the behavior - reflecting a person’s beliefs regarding the expectations of significant others about performance of particular behaviors and an individual’s motivation to comply with their significant others that can be religious leaders, family members, teachers, and friends; and

  • 3. Perceived control over the behavior (PBC) - reflecting a person’s perception regarding presence of any aid or obstacle in performing a given behavior.

The aforementioned reasons make TPB an appropriate model to study the factors related to SI during pandemic risk. Additionally, there are a lot of field where TPB has been used at a very few occasions only. One of them is willingness to self-isolate during COVID-19 pandemic. Therefore, the current study attempts at filling this research gap by considering these influencing factors of SI in the context of Saudi Arabia.

The present study aimed to explore an individual’s intention to practice SI during COVID-19 infection based on TPB. Against this backdrop, this study was conducted with the following objectives:

  • 1. To assess the willingness of general public of Sakaka, Saudi Arabia to self-isolate during COVID-19 pandemic infection;

  • 2. To apply a regression method to determine the influence of SN, ATT and PBC on individuals’ SI intention during a pandemic risk; and

  • 3. Policy recommendations for the local government.

2Methodology

Ethical clearance from the respective institute (approval no. LCBE/11-02-42) was obtained and thereafter this cross-sectional survey study was conducted.

2.1Sample population, size and characteristics

The population of Sakaka, KSA is nearly 243000 [8] that were taken into consideration while calculating the sample size. Assuming the response distribution to be 50% with 95% confidence interval and 5% margin of error, the minimum effective sample size measured for this study survey was 384. Therefore a total of 800 respondents were included to allow attrition and dropout.

2.2Study design and population

This study was conducted by using a validated self-administered questionnaire from 1st October 2020 to 1st December 2020 among the general public including patients and their accompanying persons (e.g. patient’s family members, friends, and relatives) attending the Outpatient Department of College of Dentistry, Jouf University. Other than this, the research was also conducted at the various community centers at Sakaka, KSA. Respondents were selected using a convenient sampling method. The target population was composed of adults of Sakaka city, aged≥18 years who understood English or Arabic language. Those who did not fulfil any of the aforementioned criteria were excluded from this study.

2.3Data collection tool

The questionnaire was adapted from previous study with the permission of the authors [5]. The survey questionnaire was prepared in two language versions: English and Arabic (the national language of Saudi Arabia). The English version was prepared first that was later translated into Arabic language. The study tool was piloted with 30 randomly selected subjects from the study to determine the ability of participants to understand and answer the questionnaire provided along with determining an estimate of an average time required to complete the questionnaire. To ensure content validity of the questionnaire, two senior faculty members who are expertise in survey research re-assessed the validity of the variable scales. Based on expert opinions and the findings of pilot study, some modifications of the questionnaire were done prior to the actual survey. It was also noted that each survey could be completed in approximately 7 minutes.

2.4Procedures

The selected and volunteering participants were requested to choose only one answer among the options provided. Before obtaining a verbal informed consent, the purpose of survey was briefed to them along with an assurance that the survey findings would be only published as an aggregate data maintaining the confidentiality of their personal information.

2.5Data analysis

All data was analyzed using SPSS version 20.0 (IBM Corp., Armonk, NY, USA). Descriptive statistics (mean and standard deviations) was used to summarize the data related to quantitative variables. Following this, a correlation matrix was done to assess these influences and relationships in which all the studied variables were included. Subsequently, ordinal logistic regression model was used to determine the effects of SN, PBC and ATTs on SI. The significant values of the structural model are set to p≤0.05.

3Results

Of the 800 questionnaires administered to all eligible participants, a total of 756 were completed and analyzed, giving a response rate of 94.5%. Table 1 shows the studied variables along with the descriptive statistical results. The average age of the participants was 41.4 years (range 18 to 74 years). Of all the participants, 416 (55.0%) were males and 340 (45.0%) were females. Most of the respondents had a college education or above and were married. Regarding the socio-economic status, most of participants belonged to the middle class. The average FNSC was 1.4 that means at least one member per family was in need of special care. Regarding the statement ‘How much comfortable were you during the current lockdown due to COVID-19 infection?’ 286 (37.8%) participants were ‘very much’ comfortable followed by 159 (21.0%) participants who were ‘little bit’ comfortable whereas 41 (5.4%) respondents were ‘not at all’ comfortable.

Table 1

Descriptive statistics of variables (N = 756)

VariableIndicatorsVariable descriptionn(%)Mean±SD
GenderQ1. What is your gender?1) Male416 (55.0)
2) Female340 (45.0)
AgeQ2. How old are you?1) 18– 27151 (20.0)2.95±1.38
2) 28– 37136 (18.0)
3) 38– 47196 (25.9)
4) 48– 57176 (23.3)
5) 58– 6769 (9.1)
6) Older than 6828 (3.7)
EducationQ3. What is your highest level of education?1) Primary school &below103 (13.6)
2) Secondary school95 (12.6)
3) Bachelor370 (48.9)
4) Diploma109 (14.4)
5) Master78 (10.3)
6) PhD01 (0.1)
MarriageQ4. Are you married?1) No245 (32.4)
2) Yes301 (39.8)
3) Divorced154 (20.4)
4) Widowed56 (7.4)
Socioeconomic status (SS)Q5. What level of social and economic status do you think you have?1) Upper level51 (6.7)2.81±0.80
2) Middle and upper levels145 (19.2)
3) Middle level491 (64.9)
4) Middle and lower levels34 (4.5)
5) Lower level35 (4.6)
Self-isolation (SI)Q6. How much comfortable were you during the current lockdown due to COVID-19 infection?(1) Very much286 (37.8)2.39±1.31
(2) Fine to some extent124 (16.4)
(3) Uncertain146 (19.3)
(4) Little bit159 (21.0)
(5) Not at all41 (5.4)
Attitudes toward the behavior (ATT)Q7. Do you agree or disagree with the government’s mandatory isolation people during a COVID-19 infection?(1) Strongly disagree00 (00)4.03±0.99
(2) Disagree89 (11.8)
(3) It does not matter96 (12.7)
(4) Agree272 (36.0)
(5) Strongly agree299 (39.6)
Subjective norms with respect to the behavior (SN)*Q8. If you were infected with a pandemic disease, would you let your neighbors or colleagues know?(1) Absolutely not00 (00)3.37±0.66
(2) No76 (10.1)
(3) Probably322 (42.6)
(4) Absolutely358 (47.1)
Q9. How much do you trust the infectious disease prevention information/text messages issued by the health department?(1) Strongly distrust00 (00)3.98±0.89
(2) Distrust62 (8.2)
(3) Cannot say trust or distrust119 (15.7)
(4) Trust342 (45.2)
(5) Strongly trust233 (30.8)
Perceived control over the behavior (PBC)**Q10. Do you think that COVID-19 infectious disease would have a serious impact on you or your family?(1) Not serious at all37 (4.9)3.24±0.83
(2) Not too serious62 (8.2)
(3) A little serious338 (44.7)
(4) Very serious319 (42.1)
Q11. Are you worried about COVID-19 infections?(1) Not worried at all29 (3.8)3.02±0.74
(2) Not too worried113 (14.9)
(3) A little worried429 (56.7)
(4) Very worried185 (24.5)
Q12. Do you have confidence that you can protect yourself and your family during COVID-19 infections?(1) No confidence23 (3.0)3.57±0.94
(2) Little confidence79 (10.4)
(3) Uncertain197 (26.1)
(4) Some confidence359 (47.5)
(5) Very confident98 (13.0)
Community resources (CRs)Q13. Do you agree or disagree that your community has the resources (capital/technology/materials/services,etc.) to solve community problems?(1) Strongly disagree20 (2.6)4.14±0.95
(2) Disagree29 (3.8)
(3) It does not matter87 (11.5)
(4) Agree311 (41.1)
(5) Strongly agree309 (40.9)
Emergency services (ES)Q14. If an emergency happens, do you agree or disagree that your community can provide emergency services?(1) Strongly disagree08 (1.1)3.97±0.94
(2) Disagree73 (9.7)
(3) It does not matter119 (15.7)
(4) Agree357 (47.2)
(5) Strongly agree199 (26.3)
Family members in need of special care (FNSC)Q15. Is there anyone under 18 in your family?(1) Yes503 (66.5)1.33±0.47
(2) No253 (33.5)
Q16. Is there anyone older than 60 in your family?(1) Yes544 (72.0)4.14±0.94
(2) No212 (28.0)
Q17. Is there anyone with a disability in your family?(1) Yes293 (38.8)1.28±0.45
(2) No463 (61.2)
Q18. Is there anyone with a chronic disease in your family?(1) Yes456 (60.3)1.61±0.49
(2) No300 (39.7)

*(Q8 = SNa) (Q9 = SNb) **(Q10 = PBCa) (Q11 = PBCb) (Q12 = PBCc).

3.1SI and its influencing factors

Overall, the mean score of SI in Sakaka city was 2.4 out of 5, which indicates people are between ‘fine to some extent’ and ‘uncertain’ regarding willingness to self-isolate. The results of correlation matrix are shown in Table 2 that depicts a significant association for 13 of the 14 indicators of SI especially SN, PBC and ATT that were positively related to SI.

Table 2

Correlation matrix for the studied variables in the theory of planned behavior (N = 756)

VariablesSIPBCATTSNSexAgeEducationMarriageSSCRsESChildOldDisableChronic
people
SI1
PBC– 0.306**1
ATT– 0.382**0.402**1
SN– 0.414**0.461**0.744**1
Sex– 0.174**– 0.143**– 0.120**– 0.185**1
Age– 0.160**0.271**0.272**0.195**– 0.230**1
Education0.0010.264**– 0.0180.048– 0.253**0.309**1
Marriage0.276**– 0.186**– 0.302**– 0.288**0.0360.300**0.242**1
SS– 0.104**0.183**0.0170.060– 0.0350.146**0.542**0.186**1
CRs– 0.275**0.438**0.390**0.279**– 0.0210.049– 0.083*– 0.393**– 0.0421
ES– 0.139**0.269**0.271**0.110**– 0.066– 0.061– 0.055– 0.272**– 0.135**0.633**1
Child0.323**0.085*– 0.237**– 0.184**– 0.343**0.0450.310**0.085*0.064– 0.209**– 0.094**1
Old0.163**0.022– 0.093*– 0.071– 0.120**0.0600.148**0.0360.112**– 0.157**– 0.107**0.387**1
Disable– 0.197**0.038– 0.015– 0.0420.135**– 0.0340.101**– 0.0290.309**0.057– 0.051– 0.0170.339**1
Chronic0.125**– 0.094**– 0.183**– 0.151**– 0.255**0.0170.168**0.187**0.167**– 0.153**– 0.172**0.221**0.348**0.346**1

*p < 0.05, **p < 0.01, ***p < 0.001.

The Pearson goodness-of-fit test showed that the model was not a good fit to the observed data, χ2(724) = 2785.73, p < 0.001. The deviance goodness-of-fit test illustrated that the model was not a good fit to the observed data, χ2(724) = 1373.26, p < 0.001. However, the Nagelkerke measure showed that the model explains 71.9% of the variance in the dependent. The final model significantly predicted the dependent variable over and above the intercept-only model, χ2(28) = 588.09, p < 0.001.

Subjective norms and PBC significantly (p < 0.05) influenced the intention of willingness to self-isolate, while ATT was found to be related insignificantly. The odds of letting others to know about self COVID status were 2.40 times higher than not telling the neighbors or colleagues. A statistically significant difference (p = < 0.001) existed between males and females regarding the willingness to self-isolate, with males demonstrating 2.58 times more willingness to self-isolate. Similarly the odds of willingness to self-isolate with a presence of disabled person in family were 2.88 times higher than the absence of a disability in the family. Table 3 shows the parameter estimates of ordinal linear regressions for willingness to self-isolate during the pandemic risks.

Table 3

Parameter estimates

VariableEstimateWalddfp-valueOdds95% Confidence
RatioInterval
Lower BoundUpper Bound
Age– 0.33821.7401 < 0.0010.713– 0.480– 0.196
ATT0.0830.39210.5311.087– 0.1770.343
SNa0.87714.1181< 0.0012.4040.4201.334
SNb– 0.67718.3651< 0.0010.508– 0.987– 0.367
PBCa– 0.57011.16510.0010.566– 0.904– 0.236
PBCb– 0.4439.31210.0020.642– 0.728– 0.158
PBCc0.2364.96110.0261.2670.0280.444
CRs– 0.95635.8161< 0.0010.384– 1.269– 0.643
ES0.0190.02110.8861.019– 0.2420.281
Gender
  Males0.95120.0481< 0.0012.5870.5341.367
  Females0a01.000
Education
  Primary school &below– 1.5940.73110.3920.203– 5.2482.060
  Secondary school– 0.3100.02810.8670.734– 3.9343.315
  Bachelor– 1.1080.36610.5450.330– 4.6982.482
  Diploma– 0.2240.01510.9030.799– 3.8373.388
  Master– 1.6260.77410.3790.197– 5.2481.996
  PhD0a01.000
Marriage
  No– 1.89016.7031< 0.0010.151– 2.796– 0.984
  Yes– 0.0440.01110.9170.957– 0.8730.785
  Divorced– 0.0670.02710.8700.936– 0.8680.734
  Widowed0a01.000
Social status
  Upper level– 1.1584.74310.0290.314– 2.200– 0.116
  Middle and upper levels– 2.71827.9441< 0.0010.066– 3.726– 1.710
  Middle level– 3.05248.4571< 0.0010.047– 3.911– 2.192
  Middle and lower levels– 2.16615.6231<0.0010.115– 3.240– 1.092
  Lower level0a01.000
Is there anyone under 18 in your family?
  Yes– 0.94621.2021 < 0.0010.388– 1.349– 0.544
  No0a01.000
Is there anyone older than 60 in your family?
  Yes– 0.80014.2591 < 0.0010.449– 1.215– 0.385
  No0a01.000
Is there anyone with a disability in your family?
  Yes1.05923.2241 < 0.0012.8830.6281.489
  No0a01.000
Is there anyone with a chronic disease in your family?
  Yes0.2351.39010.2381.264– 0.1550.625
  No0a01.000

aThis parameter is set to zero because it is redundant.

4Discussion

The findings of the current research are evident to support the TPB as an efficient predictor of people’s behavior for willingness to self-isolate during COVID-19 pandemic. Among the three influential factors, SN plays the most important role followed by PBC and ATT. This finding is consistent with the previous studies where SN and PBC were found to the better predictor of the said behavioral intentions although PBC variables were typically less important than SN [4, 5, 9– 16]. In contrast, few of the previous studies opined the influences of ATT and PBC on establishing an intention to be stronger than the influence of SN [6, 17– 24].

For SN, a significant result was observed where the respondents strongly agreed in letting the neighbors or colleagues know about an individual’s being positive for COVID-19 infection. This behavior could be either due to individuals’ fear that they might spread the disease to their dear ones or could be due to the possible social pressures because an individual who does not follow such normative actions receives blame from others and immediately becomes the public enemy [25, 26].

As shown in this study, an average attitude to willingly self-isolate during the pandemic risk might be attributed to the fact that individuals may believe that the spread of an infection is not reduced only by restricting themselves at home and avoiding gatherings but rather regularly washing hands using soap and water or with hand sanitizers, eating healthy foods and covering the nose and mouth while sneezing or coughing along with strictly following social distancing as suggested by WHO [27]. Also, the significance of the TPB factors for the prediction of behavior intention varies according to the target population and behavior [28].

This study further investigated the relationship between individual’s age, gender, level of education, marital status, and economic status and found that younger respondents demonstrated a more positive intention for SI. These results were consistent with recent studies where the younger participants showed a positive intention towards the said behavior [5, 6, 29]. In the current study, gender had a significant difference on willingness to self-isolate with males showing more willingness as compared to the females. The crisis might aggravate gender inequality especially for working mothers as they might have suffered a severe physical and emotional distress from being overloaded with childcare due to school closure while do multitasking [16]. Additionally, the females might be depressed due to the pandemic that has lasted longer than anticipated. Similar results were found in previous studies where differences in behavioral changes between males and females was noted [30, 31] whereas another recent study found no significant difference between males and females in their behavioral change [5].

In the present study, a statistically significant difference was noticed between unmarried and widowed participants, with unmarried participants showing more willingness to self-isolate that is contradictory to the finding of a previous study where being married had a significant positive effect on SI [5]. This could be due to the fact that under risk circumstances, the herding behavior (i.e. referring to others’ opinions in decision-making) of an unmarried individual could be more salient to minimize anxiety from uncertainty [32]. In the present study, willingness to self-isolate was seen to be reduced in upper social status, upper middle, middle and lower middle social status. It is a well-established fact that people belonging to such groups have less chances of social distancing due to cramped spaces which limits the resources to self-isolation, leading to more chances of infection. Diabetes and hypertension are also prevalent amongst such groups which complicate the outcomes once the person is infected [33]. In contrast to previous studies, the experience of the authors of this study had been different; in fact it was seen that high socio-economic status is a poor indicator for higher willingness for self-isolation [5].

Education and emergency services did not appear as a significant predictor variable for willingness to self-isolate in this study; in contrast with a recent study where a higher educational level among the participants and the availability of emergency services had a significant positive influence on SI [5]. Conversely, community resources are not useful for SI which is in line with the findings from previous studies as well [4, 5]. One possible explanation could be that the community will be more resilient if a community has more resources like food, money and technology that will eventually lead to an individual’s less willingness to self-isolate because a person believes that the community will manage the risk related to an contagious infection.

For FNSC, the effects on SI of having a family member who has a disability or a chronic disease were positive, meaning that such individuals may have more willingness to self-isolate. This finding could be attributed to the fact that a family having a member who has any co-morbidity may be well aware of the medical emergencies with a better understanding of the dangers related to a pandemic. On the other hand, the effect of having a family member who is old or those in a family with a child was significant and negative, showing a lower willingness to self-isolate.

4.1Policy recommendations for the government

It is highly appreciable the way the Saudi government has managed to curb the spread of the novel coronavirus. Early lockdown with phased interventions at various levels with restriction on mass gatherings and the population movement is a lustrous example of a bureaucracy which is socially responsible. A continuous creation of awareness amongst the community through recurring messages on mobile phones and innovative ideas to catch the attention of denizens has been an effective tool initiated by health care authorities of Saudi Arabia [34, 35]. Although the authorities in Saudi Arabia have left no stone unturned to achieve these goals but the findings of the current study identifies few important aspects that the government needs to take care when encouraging citizens to self-isolate during a pandemic situation. Firstly, an early warning system about pandemic emergencies should be provided that will significantly enhance the compliance with public health preventive measures like self-isolation and will subsequently improvise an individual’s attitude to self-isolate during the pandemic risk. Although, the preventive measures like self-isolation and quarantine definitely impinges upon individuals’ rights and freedoms other than imposing considerable economic and social distress as well but an early warning provided to the people will make them well-aware that an elimination of even a minute number of infected individuals from the general population is likely to be beneficial from the standpoint of community health.

Secondly, sufficient training regarding the better public services should be provided to citizens that will possibly reduce the difficulty of applying health behavior; otherwise, adherence to preventive measures may be low. The behavioral control improves when an individual is well-aware of the use of preventive items like face masks and sanitizers and confidently follows the preventive interventions.

It’s needless to say that any organization with social responsibilities will find it difficult to manage the issues ranging from social, physical and mental health of the people; to the education, health care and daily needs. Through this study authors have tried to sum up all the factors that can challenge the government to enforce self-isolation amongst the general population of Saudi Arabia during the COVID-19 pandemic.

5Limitations

The limitation is that since all the data were from one city of Northern part of Saudi Arabia, the findings may not be applicable for the population outside this geographic area and generalizations of the findings are, thus, limited.

6Conclusion

The study provides a timely and meaningful understanding of the level of the public’s behavior when facing a pandemic such that it can be used to target policy interventions needed to curtail the spread of COVID-19 infection. As informed by the health authorities, there is an urgent need to prepare for the second wave of the COVID-19 crisis; hence, the findings of this study might offer a significant reference point for follow-up longitudinal studies to assess an individual’s short-term and long-term behavioral changes. Additionally, this study may add to the literature, as it explores notions of behavioral changes during a pandemic period.

Author contributions

Conceptualization: Dr. Rakhi Issrani, Dr. Mohammad Khursheed Alam. Methodology and formal analysis: Dr. Rakhi Issrani. Data curation: Dr. Rakhi Issrani. Literature search: Dr. Rakhi Issrani. Writing - original draft preparation: Dr. Rakhi Issrani. Writing - review and editing: Dr. Mohammad Khursheed Alam. Final approval of the version to be published: Dr. Rakhi Issrani, Dr. Mohammad Khursheed Alam.

Conflict of interest

The authors declare no conflict of interest.

Data availability

The data set used in the current study will be made available on request from Dr. Rakhi Issrani; .

Funding

The authors extend their appreciation to the Deanship of Scientific Research at Jouf University, Kingdom of Saudi Arabia, for funding this work through research grant no. CV-24-41 in April 2020.

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