Affiliations: Hacettepe University, Faculty of Education, Department of Physics Education, Beytepe 06800, Ankara, Turkey | Institute of Nuclear Sciences, Hacettepe University, Beytepe 06800, Ankara, Turkey | JASRI/SPring-8, Kouto, Sayo, Hyogo 679-5198, Japan | Baskent University, School of Medicine, Department of Pathology, Bahcelievler 06490, Ankara, Turkey | Gulhane Medical Academy, Department of Orthopedic, Etlik 06018, Ankara, Turkey
Note: [] Corresponding author: Sevgi Haman Bayarı, Hacettepe University, Faculty of Education, Department of Physics Education, Beytepe 06800, Ankara, Turkey. Tel.: +90 312 297 86 06; Fax: +90 312 297 86 00; E-mail: [email protected]
Abstract: Avascular necrosis (osteonecrosis) is a disease that results from the temporary or permanent loss of blood supply to the bone. Synchrotron FT-IR microspectroscopy has been used to study the changes in mineral and matrix content of necrotic bone. FT-IR spectroscopic analysis revealed that in necrotic bone the relative mineral/matrix ratio decreased. Spectroscopic differences were observed between normal and necrotic bones. The noticeable differences may have important implications for analyzing and evaluating death bone.
