Affiliations: Department of Physics, Faculty of Science, University of Dicle, 21280 Diyarbakır, Turkey | Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Dicle, 21280 Diyarbakır, Turkey
Note: [] Corresponding author: Hatice Budak, Assistant professor, Department of Physics, Faculty of Science, University of Dicle, 21280 Diyarbakır, Turkey. Tel.: +90 412 2488050 (3127); Fax: +90 412 2488039; E-mail: [email protected].
Abstract: Macromolecular crowding is a general phenomenon of biological systems, and the evaluation of a correlation time for a specific molecule is difficult when the molecular crowding exists. The determination of an effective correlation time may therefore give useful insights into molecular dynamics of such systems. In this work, the relaxation rates in the mixture of D2O (80%) and cystic fluid (20%) were measured with a NMR operating at 400 MHz for three types of cysts (non-infected radicular, infected radicular and hemorrhagic). The effective correlation times (τ values) were then determined by using a formula derived from the observed relaxation rates. The τ value of the infected cyst was found to be longer than those of the others for the studied cases. The present data suggest that an effective correlation time for fluids with macromolecular crowding can be determined from NMR relaxation measurements.
Keywords: Correlation time, relaxation time, cysts and NMR
Journal: Spectroscopy, vol. 20, no. 4, pp. 177-183, 2006
