Affiliations: [a]
Department of Otolaryngology Teikyo University School of Medicine Mizonokuchi Hospital, Kawasaki, Japan
| [b] Yoshimura ENT Clinic, Fujisawa, Japan
Correspondence:
[*]
Corresponding author: Prof. Toshihisa Murofushi MD PhD, Department of Otolaryngology Teikyo University School of Medicine Mizonokuchi Hospital, 5-1-1 Futago Takatsu-ku Kawasaki 213-8507 Japan. Tel.: +81 44 844 3333; Fax: +81 44 844 3273; E-mail: [email protected].
Abstract: BACKGROUND:There are only a few reports concerning cervical vestibular evoked myogenic potential (cVEMP) using chirp sound, and clinical indications/advantages of it are still unclear. OBJECTIVE:To compare cVEMP using CE-chirp LS® with cVEMP using 500 Hz and 1000 Hz tone bursts (TB) and to investigate clinical indications/advantages of CE-chirp LS® for recording cVEMP. METHODS:Sixteen patients with vestibular disorders (2men and 14 women) (18∼62, mean 42.9 years of age) were enrolled in this study. Participants underwent cVEMP testing using 500 Hz and 1000 Hz tone bursts (TB) and CE-chirp LS®. Response rate of P1-N1, corrected/normalized amplitude of P1-N1, latencies of P1 and N1, asymmetry ratio, and correlation of P1 latency to SLOPE in tuning property test (an index of endolymphatic hydrops) were compared. RESULTS:Corrected/normalized amplitude of P1-N1 to CE-chirp LS® was smaller than corrected/normalized amplitude of P1-N1 to 500 Hz TB. Peak latencies to CE-chirp LS® were the shortest among the 3 types of stimulation. EH-positive ears according to the tuning property test had tendency of prolonged P1 latencies to CE-chirp LS®. CONCLUSION:CE-chirp LS® is applicable for recording cVEMP with a similar diagnostic accuracy to TB. Prolongation of P1 latency in CE-chirp LS® might be an indicator of endolymphatic hydrops in the saccule.
