The effectiveness of plasma expanders, an osmotic pressure and viscosity study¹

Article type: Research Article

Authors: Cerny, L.C.^{; *} | Grauz, J.D.^{; **} | James, H.^{; ***}

Affiliations: Masonic Medical Research Laboratory, Utica College of Syracuse University, Utica, New York 13501

Note: [1] Supported by American Heart Association Grant No. 62E4 and PHS 65-222.

Note: [*] Established Investigator of the American Heart Association.

Note: [**] Present address: Department of Biophysics, University of Chicago, Chicago, Illinois.

Note: [***] Present address: General Tire and Rubber Company, Akron, Ohio.

Abstract: The osmotic pressures of mixtures containing albumin, various dextrans and one hydroxyethyl starch sample were determined. The interaction coefficient was calculated in order to access the effectiveness of these plasma expanders as osmotic colloidal agents. A series of commercially prepared hydroxyethyl starch solutions was used in a viscometric evaluation of cell-protein interactions with resuspended red cells at low shear rates.

DOI: 10.3233/BIR-1968-5202

Journal: Biorheology, vol. 5, no. 2, pp. 103-110, 1968