Two-layered blood flow in stenosed tubes for different diseases

Issue title: 25th Anniversary Volume

Article type: Research Article

Authors: Pralhad, R.N. | Schultz, D.H.

Affiliations: Department of Mathematical Sciences, University of Wisconsin-Milwaukee, Milwaukee, WI 53201, U.S.A.

Note: [] Accepted by: Editor P. Riha

Abstract: A two-fluid model for blood flow through a stenosed tube has been developed. The model consists of a core (suspension of RBCs) and peripheral plasma layer. The core is assumed to be represented by a polar fluid and the plasma layer by a Newtonian fluid. The flow is assumed to be steady and laminar, and the fluids incompressible. The flow variables are computed for normal blood and for the cases of polycythemia, plasma cell dyscrasias and for Hb SS diseases. Resistance to flow has been computed for different stenosis length and for different stenosis height. Shear stress distribution along the axial distance has been computed for different stenosis height. The impact of size effects (particle size to tube diameter) on blood diseases is discussed.

Keywords: Blood flow, stenosis, two-fluid model, polar fluid, Hemodynamics, Hemorheology, microcirculation

DOI: 10.3233/BIR-1988-25501

Journal: Biorheology, vol. 25, no. 5, pp. 715-726, 1988