About the importance of account of some microcirculation parameters dispersion in modelling oxygen transport

Issue title: Proceedings of the Fourth International Congress of Biorheology. Jikei University School of Medicine, Tokyo, Japan, 27 July – 1 August 1981. Dedicated to Alex Silberberg

Guest editors: Alfred L. Copley

Article type: Research Article

Authors: Sharikov, Alexander N. | Zaiko, Valery M.

Affiliations: Laboratory of Biomechanics, Institute of Transplantology and Artificial Organs, 2/3 Pehotnaya St., P.O. 123436; Moscow, U.S.S.R.

Note: [] Accepted by: Editor Y.C. Fung

Abstract: During the recent years various investigators have developed the technique of kryophotometric measurements of oxyhemoglobin saturation with oxygen (Ψ) in small vessels. In this paper, on the basis of the statistical model of the organ developed by the authors, a theoretical relationship is established between the distributions of measured in various groups of experiments in the capillaries and the distributions of Ψ in the arterioles and venules. It is shown that for the description of the distribution of Ψ in a separate multicapillary unit, lying between the arteriole and the venule, it is possible to introduce a special distribution function. In some cases this function may be determined analytically. Statistical distributions of other microcirculation parameters may be included into the statistical model of the organ using the similar procedure described in this paper for the parameters Ψa, Ψv-arteriolar and venular Ψ.

Keywords: Microcirculation, Oxygen transport

DOI: 10.3233/BIR-1982-191-235

Journal: Biorheology, vol. 19, no. 1-2, pp. 331-339, 1982