Searching for just a few words should be enough to get started. If you need to make more complex queries, use the tips below to guide you.
Issue title: The Proceedings of the 3rd International Conference on Food Factors (ICoFF 03)
Article type: Research Article
Authors: Mukai, Rie | Fukuda, Itsuko | Nishiumi, Shin | Hosokawa, Keizo | Kanazawa, Kazuki | Ashida, Hitoshi
Affiliations: Laboratory of Food and Nutritional Chemistry, Faculty of Agriculture, Kobe University, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo 657-8501, Japan | Department of Nutrition Management, Faculty of Health Science, Hyogo University, 2310 Shinzaike, Hiraoka-cho, Kakogawa, Hyogo 675-0195, Japan
Note: [] Corresponding author. Tel./Fax: +81 78 803 5878; E-mail: [email protected]
Abstract: Dioxins cause a variety of toxic effects through transformation of a cytosolic aryl hydrocarbon receptor (AhR). We have previously demonstrated that certain natural flavones and flavonols at the dietary levels suppress AhR transformation. In this study, we investigated whether 5 anthocyanidins, 15 anthocyanins, and protocatechuic acid suppress AhR transformation in mouse hepatoma Hepa-1c1c7 cells. All the compounds tested here at 5 μM unexpectedly failed to suppress the transformation induced by 0.1 nM TCDD, indicating that anthocyan does not have a potential to prevent dioxin toxicity.
Keywords: anthocyan, dioxin, aryl hydrocarbon receptor
Journal: BioFactors, vol. 21, no. 1-4, pp. 371-373, 2004
IOS Press, Inc.
6751 Tepper Drive
Clifton, VA 20124
USA
Tel: +1 703 830 6300
Fax: +1 703 830 2300
[email protected]
For editorial issues, like the status of your submitted paper or proposals, write to [email protected]
IOS Press
Nieuwe Hemweg 6B
1013 BG Amsterdam
The Netherlands
Tel: +31 20 688 3355
Fax: +31 20 687 0091
[email protected]
For editorial issues, permissions, book requests, submissions and proceedings, contact the Amsterdam office [email protected]
Inspirees International (China Office)
Ciyunsi Beili 207(CapitaLand), Bld 1, 7-901
100025, Beijing
China
Free service line: 400 661 8717
Fax: +86 10 8446 7947
[email protected]
For editorial issues, like the status of your submitted paper or proposals, write to [email protected]
如果您在出版方面需要帮助或有任何建, 件至: [email protected]