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Article type: Research Article
Authors: Yoshikawa, Kenichia; * | Mizukami, Masafumib | Kawamoto, Hiroakic | Sano, Ayumua | Koseki, Kazunoria | Sano, Kumikoa | Asakawa, Yasutsugub | Kohno, Yutakad | Nakai, Keid; e | Gosho, Masahikof | Tsurushima, Hideoe
Affiliations: [a] Department of Physical Therapy, Ibaraki Prefectural University of Health Sciences Hospital, Ami Ibaraki, Japan | [b] Department of Physical Therapy, Ibaraki Prefectural University of Health Sciences, Ami Ibaraki, Japan | [c] Faculty of Systems and Information Engineering, University of Tsukuba, Tsukuba Ibaraki, Japan | [d] Department of Neurology, Ibaraki Prefectural University of Health Sciences Hospital, Ami Ibaraki, Japan | [e] Faculty of Medicine, University of Tsukuba, Tsukuba Ibaraki, Japan | [f] Department of Clinical Trial and Clinical Epidemiology, Faculty of Medicine, University of Tsukuba, Tsukuba Ibaraki, Japan
Correspondence: [*] Address for correspondence: Kenichi Yoshikawa, 4733 Ami, Ami-Machi, Inashiki-County, Ibaraki 300-0394, Japan. Tel.: +81 29 888 9216; Fax: +81 29 888 9279; E-mail: [email protected].
Abstract: BACKGROUND: The robotic Hybrid Assistive Limb (HAL) provides motion according to the wearer’s voluntary activity. HAL training effects on walking speed and capacity have not been clarified in subacute stroke. OBJECTIVES: To determine improvement in walking ability by HAL and the most effective improvement measure for use in future large-scale trials. METHODS: Sixteen first-ever hemiplegic stroke patients completed at least 20 sessions over 5 weeks. Per session, the experimental group received no more than 20 min of gait training with HAL (HT) and 40 min of conventional physiotherapy, whereas the control group received at least 60 min of conventional physiotherapy. Primary outcome was maximum walking speed (MWS). RESULTS: The change in MWS from baseline at week 5 was 11.6±10.6 m/min (HAL group) and 2.2±4.1 m/min (control group) (adjusted mean difference = 9.24 m/min, 95% confidence interval 0.48–18.01, P = 0.040). In HAL subjects there were significant increases in Self-selected walking speed (SWS; a secondary outcome) and in step length (a secondary outcome) at MWS and SWS compared with controls. CONCLUSIONS: HT improved walking speed in hemiplegic sub-acute stroke patients. In future, randomized controlled trials are needed to confirm the utility of HT.
Keywords: Hybrid Assistive Limb, robot-assisted gait training, stroke
DOI: 10.3233/NRE-161393
Journal: NeuroRehabilitation, vol. 40, no. 1, pp. 87-97, 2017
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