“Chromosome”: a knowledge-based system for the chromosome classification

Article type: Research Article

Authors: Ramstein, G.^{; *} | Bernadet, M.

Affiliations: L.A.T.I./Ireste La Chantrerie CP 3003–44087 Nantes France

Correspondence: [*] Corresponding author, Tel: 33.40.68.30.44 Fax: 33.40.68.30.66.

Abstract: Chromosome, a knowledge-based analysis system has been designed for the classification of human chromosomes. Its aim is to perform an optimal classification by driving a tool box containing the procedures of image processing, pattern recognition and classification. This paper presents the general architecture of Chromosome, based on a multiagent system generator. The image processing tool box is described from the met aphasic enhancement to the fine classification. Emphasis is then put on the knowledge base intended for the chromosome recognition. The global classification process is also presented, showing how Chromosome proceeds to classify a given chromosome. Finally, we discuss further extensions of the system for the karyotype building.

Keywords: Chromosome analysis, Knowledge-based system, Image analysis

DOI: 10.3233/THC-1993-1208

Journal: Technology and Health Care, vol. 1, no. 2, pp. 171-180, 1993