Design of spherical carbon adsorbent for extracorporeal detoxification

Article type: Research Article

Authors: Rosinski, S.^{a; *} | Sentek, J.^b | Lewinska, D.^a

Affiliations: [a] Institute of Biocybernetics and Biomedical Engineering of PAS, Warsaw, Poland | [b] Institute of Inorganic Chemistry, High Technical School, Warsaw, Poland

Correspondence: [*] Correspondence to: Stefan Rosinski, Institute of Biocybernetics and Biomedical Engineering of PAS, ul. Trojdena 4, 02 109, Warszawa, Poland.

Abstract: A special carbon adsorbent (CA), designed for use in extracorporeal detoxification by hemoperfusion, was produced from a spherical synthetic polymer by our own technolique and tested at a preclinical level. Comparison of mechanical properties, sorption and biocompatibility between CA and medical hemosorbents was made. The carbon adsorbent is hard, has a smooth surface, shows good sorption properties and has acceptable biocompatibility. These features qualify the carbon adsorbent for use in clinical hemoperfusion without any additional membrane coating.

Keywords: Hemoperfusion, Hemosorbent, Carbon adsorbent

DOI: 10.3233/THC-1993-1205

Journal: Technology and Health Care, vol. 1, no. 2, pp. 155-158, 1993