Affiliations: Italian Medicines Agency (AIFA), Rome, Italy. E-mail:
[email protected]
Abstract: In the past, drug discovery developed in an environment where
resources in healthcare where believed to be adequate, and all patients
affected by a given disease where considered similar, therefore in need of a
similar treatment. However, these concepts are no longer valid, and the present
reality shows that current circumstances are characterised by limited financial
resources in the presence of always growing expectations. In addition, current
research trend is progressing toward the identification of novel molecular
targets and a personalised medicine approach.
Keywords: Innovation, R&D expenditure, risk-sharing, Italian Medicines Agency