Affiliations: [a] Department of Radiology, the First Affiliated Hospital of Nanjing Medical University, Guangzhou Road, Nanjing, Jiangsu, China
| [b] Department of Radiology, Liyang people’s hospital, Jianshe West Road, Liyang, Jiangsu, China
Correspondence:
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Corresponding author: Xiaomei Zhu, MD, PhD, Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, No. 300, Guangzhou Rd., Nanjing, China. Tel.: +86 13770346260 –Ext: 210029; E-mail: [email protected].
Abstract: BACKGROUND:Accuracy of CT-derived fractional flow reserve depends on good image quality. Thus, improving image quality during coronary CT angiography (CCTA) is important. OBJECTIVE:To investigate impact of respiratory motion artifact on coronary image quality focusing on vessel diameter and territory during one beat CCTA by a 256-row detector. METHODS:We retrospectively reviewed patients who underwent CCTA under free-breathing (n = 100) and breath-holding (n = 100), respectively. Coronary image quality is defined as 4-1 from excellent to poor (non-diagnostic) and respiratory motion artifact severity is also scored on a 4-point scale from no artifact to severe artifact. Coronary image quality and respiratory motion artifact severity of all images were evaluated by two radiologists independently. RESULTS:Compared with free-breathing group, the image qualities are significantly higher in per-segment, per-vessel and per-patient levels (P < 0.001) and proportion of segments with excellent image quality also improves significantly (73.6% vs 60.1%, P < 0.001) in breath-holding group. The image quality improvement occurs in medium-sized coronary arterial segments. Coronary image quality improves with respiratory motion artifacts decreasing in both groups, respectively. CONCLUSION:During one heartbeat CCTA, breath-holding is still recommended to improve coronary image quality due to improvement of the image quality in the medium-sized coronary arteries.
