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Article type: Research Article
Authors: Lau, Andy | Chen, Yong | Ahmad, Salahuddin
Affiliations: Department of Radiation Oncology, Peggy and Charles Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA
Note: [] Corresponding author: Salahuddin Ahmad, Department of Radiation Oncology, Peggy and Charles Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, 800 N.E. 10th St., OKCC L100, Oklahoma City, OK 73104, USA. Tel.: +1 405 271 3016; Fax: +1 405 271 8297; E-mail: [email protected]
Abstract: In-vivo range verification systems for incident protons recently utilize positron emission tomography (PET) based on the phenomenon of positron-emitting nuclei (PEN). However, recent investigations are suggesting that the range can be verified also from the prompt gamma (PG) photon emissions generated from proton interactions. In this work we investigate using the Geant4 Monte Carlo toolkit the clinical viability of a theoretical sequential detector system to verify the range of protons in proton radiotherapy by the PG method for simple geometries and beam configurations. The results show a correlation between selected emitted PG rays and the incident protons range and suggest that our detector system is capable of in-vivo range monitoring for energies typical of radiation oncology applications. Future work will include implementing more realistic scenarios and optimizing current detector parameters.
Keywords: Prompt gamma, Geant4 simulation, radiation therapy
DOI: 10.3233/XST-130399
Journal: Journal of X-Ray Science and Technology, vol. 21, no. 4, pp. 507-514, 2013
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