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Article type: Research Article
Authors: He, Peng; | Yu, Hengyong; | Thayer, Patrick | Jin, Xin | Xu, Qiong | Bennett, James | Tappenden, Rachael | Wei, Biao | Goldstein, Aaron | Renaud, Peter | Butler, Anthony | Butler, Phillip | Wang, Ge;
Affiliations: The Key Lab of Optoelectronic Technology and System of the Education Ministry of China, Chongqing University, Chongqing, China | Biomedical Imaging Division, VT-WFU School of Biomedical Engineering and Sciences, Virginia Technology, Blacksburg, VA, USA | Department of Radiology, Division of Radiologic Sciences, Wake Forest University Health Sciences, Winston-Salem, NC, USA | Biomedical Imaging Division, VT-WFU School of Biomedical Engineering and Sciences, Wake Forest University Health Sciences, Winston-Salem, NC, USA | Department of Mathematics and Statistics, University of Canterbury, Private Bag, Christchurch, New Zealand | Department of Radiology, University of Otago, Christchurch, New Zealand | Department of Physics and Astronomy, University of Canterbury, Private Bag, Christchurch, New Zealand
Note: [] Corresponding author. E-mail: [email protected]; [email protected]
Abstract: The Medipix All Resolution System (MARS) system is a commercial spectral/multi-energy micro-CT scanner designed and assembled by the MARS Bioimaging, Ltd. in New Zealand. This system utilizes the state-of-the-art Medipix photon-counting, energy-discriminating detector technology developed by a collaboration at European Organization for Nuclear Research (CERN). In this paper, we report our preliminary experimental results using this system, including geometrical alignment, photon energy characterization, protocol optimization, and spectral image reconstruction. We produced our scan datasets with a multi-material phantom, and then applied ordered subset-simultaneous algebraic reconstruction technique (OS-SART) to reconstruct images in different energy ranges and principal component analysis (PCA) to evaluate spectral deviation among the energy ranges.
Keywords: Spectral/Multi-Energy Micro-CT, OS-SART, multi-material phantom, PCA
DOI: 10.3233/XST-2012-0329
Journal: Journal of X-Ray Science and Technology, vol. 20, no. 2, pp. 199-211, 2012
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