Affiliations: National Institutes of Health, National Institute of
Child Health and Human Development, Laboratory of Integrative and Medical
Biophysics, Bethesda, MD, USA | University of Maryland, Department of Biological
Resources Engineering, College Park, MD, USA | Tel-Aviv University, Department of Biomedical
Engineering, Tel-Aviv, Israel
Note: [] Corresponding author: National Institutes of Health, 9000
Rockville Pike, Building 9 Room B1E05, Bethesda, MD 20892, USA. Tel.: +1 301
402 0648; Fax: +1 301 480 2427; E-mail: [email protected]
Abstract: This paper describes a few optical imaging methods in their
translational stage to the clinical phase. The methods are compared to
well-established X-ray imaging methods such as computed tomography and
mammography. The drawback of the diffuse paths of laser photons compared to the
ballistic paths of the X-ray is compensated by coherence methods for tissue
characterization adjacent to the surface, and acoustic wave enhanced imaging
and fluorescent markers that follow functional changes when deeper tissue is
analyzed. This paper presents some of the latest developments in this field as
presented in a Bench to Bedside workshop on optical imaging held at the
National Institutes of Health.
