A child with XYY karyotype and epilepsy

Article type: Research Article

Authors: Değerliyurt, Aydan | Ceylaner, Gülay | Ceylaner, Serdar

Affiliations: Department of Pediatric Neurology, Ankara Dışkapı Children's Hospital, Ankara, Turkey | Intergen Genetics Center, Ankara, Turkey

Note: [] Correspondence: Dr. Aydan Değerliyurt, Bebek sok, 9/7 Aydınlıkevler, Ankara, Turkey. Tel.: +90 312 596 96 51; Fax: +90 312 347 23 30; E-mail: [email protected]

Abstract: The XYY chromosome abnormality is a frequently encountered numerical chromosome abnormality characterized by behavioral problems, developmental retardation and average or lower than average intelligence. A strong association with epilepsy has not been reported for the XYY anomaly unlike other chromosomal abnormalities where concurrence with seizures or epilepsy has been reported in a few studies. In this manuscript, we describe a patient with XYY karyotype, mild mental retardation and epilepsy.

Keywords: Chromosome XYY abnormality, epilepsy, mild mental retardation

DOI: 10.3233/JPN-2011-0479

Journal: Journal of Pediatric Neurology, vol. 9, no. 2, pp. 255-258, 2011