Affiliations: Department of Pediatrics, University of Michigan
Medical School, Ann Arbor, MI, USA | Department of Pediatric Neurology, Neurosciences
Centre, King Fahad Medical City, Riyadh, Saudi Arabia
Note: [] Correspondence: Dr. Tamer Rizk, M.D., Department of Pediatric
Neurology, Neurosciences Centre, King Fahad Medical City, Riyadh, Saudi Arabia.
Tel.: +966 12889999; Ext: 1766; Fax: +966 12889999; Ext 1982; E-mail:
[email protected]
Abstract: Dystonia is a syndrome of sustained muscular contractions of
opposing muscles with various etiologies. The currently available symptomatic
treatment strategies are quite effective for some of the various types of
dystonia. They help in decreasing involuntary movements, correcting abnormal
posture, preventing contractures, reducing pain, improving function and quality
of life. Intrathecal baclofen and deep brain stimulation were proved to be
fairly effective in controlling dystonia when used separately. We are reporting
a synergetic effect of intrathecal baclofen and deep brain stimulation when
used simultaneously in two cases of primary generalized dystonia with excellent
control of dystonia.
Keywords: Dystonia, intrathecal baclofen, deep brain stimulation