Affiliations: Department of Radiodiagnosis, Maulana Azad Medical
College and Associated Lok Nayak Hospital, Jawaharlal Nehru Marg, New Delhi,
India
Note: [] Correspondence: Dr. Vivek C. Kottiyath, Department of
Radiodiagnosis, Maulana Azad Medical College and Associated Lok Nayak Hospital,
Jawaharlal Nehru Marg, 110002, New Delhi, India. Tel.: +9111 27186800; Fax:
+9111 47111142; E-mail: [email protected]
Abstract: We report brain magnetic resonance imaging findings in three infants
who had severe neonatal hyperbilirubinemia, and presented later on with
different neurological manifestations. Two children presented at 6~months of
age with global developmental delay, dystonia and hearing impairment. The third
child presented with developmental delay, nystagmus and superior gaze palsy at
ten months of age. The history and clinical picture suggested sequelae of
bilirubin encephalopathy (kernicterus). Magnetic resonance imaging of the brain
in all the patients revealed hyperintensity in bilateral globus pallidus on
T2-weighted images. Increased apparent diffusion coefficient values were
observed in the affected regions on diffusion-weighted imaging, which has not
been reported previously.
