Affiliations: Department of Pediatric Neurology, Children's
Hospital, Leicester Royal Infirmary, University Hospital of Leicester NHS
Trust, Leicester, UK
Note: [] Correspondence: Dr. Nahin Hussain, %Consultant Pediatric
Neurologist, Children's Hospital, Leicester Royal Infirmary, University
hospitals of Leicester NHS trust, Leicester LE1 5WW, UK. Tel.: +44 1162587760;
Fax: +44 1162587637; E-mail: [email protected]
Abstract: Cerebral sinovenous thrombosis (CSVT) is a rare and under-diagnosed
complication of ulcerative colitis. We report a case of a 14-year-old male
child, who presented with a history of worsening headaches, vomiting and
decreased level of consciousness. He was diagnosed to have CSVT with infarction
on magnetic resonance imaging of the brain. He was treated with low molecular
weight heparin and discharged home with a mild right-sided hemiparesis. At a
year follow-up, his neurological examination was normal. The use of
antithrombotic therapy, in particular low molecular weight heparin can be
effective in reducing the mortality and morbidity associated with CSVT.
Nevertheless, randomized placebo-controlled studies are necessary for assessing
its efficacy and absence of risk in children.