Abstract: The aim of this case-control study was to determine whether there is
any association between idiopathic generalized epilepsy and allergic disorders
in children. All children with idiopathic epilepsy attending the Motahary
Clinic, Shiraz, Iran, in a 7-month period were included in the study.
Neurologically normal children, matched for age and sex, were considered as
controls. The required data including age, gender, history of allergic
disorders, history of smoking in the family members and breast versus formula
feeding in the first six months of life were collected. The total number of
participants was 110 patients and 100 controls. History of allergic disorders
was positive in 28.2% of the patients and 36% of the controls (P=0.225). When
only patients with idiopathic generalized epilepsy were considered
(100 patients), allergic disorders were reported in 28%. The prevalence of
allergic disorders in patients with idiopathic generalized epilepsy was not
significantly different from that in controls (P=0.225). Family history of
allergic disorders was positive in 34.5% of the patients and 45% of the
controls (P=0.122). Our study failed to demonstrate any association or link
between idiopathic generalized epilepsy and allergy.
