Affiliations: Unidad de Salud Mental Infanto-Juvenil, Servicio de
Psiquiatría y Psicología, Cantabria, Spain
Note: [] Correspondence: Soraya Otero, MD, PhD, Unidad de Salud Mental
Infanto-Juvenil, Servicio de Psiquiatría y Psicología, Hospital
Universitario Marqués de Valdecilla, C/L.V. de Velasco
n^o1, 39011, Santander, Cantabria, Espaňa. E-mail:
[email protected], [email protected]
Abstract: This paper describes a 14-year-old boy presenting both
extrapyramidal syndrome and a depressive episode after the initiation of
flunarizine treatment for migraine. A detailed case history was obtained using
traditional assessment and a semi-structured interview. A Medline search was
done for information on adverse effects of flunarizine and co-morbidity between
migraine and anxiety-depression symptoms. Some patients could have a
predisposition to anxiety-depression as a global response. The intake of
certain drugs, such as flunarizine, affecting central receptors, could
precipitate the onset of depressive symptoms.
