Affiliations: Department of Pediatrics, RWTH, University Hospital
Aachen, Aachen, Germany | Department of Virology, RWTH, University Hospital
Aachen, Aachen, Germany
Note: [] Correspondence: Christian Denne, MD, Department of Pediatrics,
RWTH University Hospital Aachen Pauwels street 30, 52064 Aachen, Germany. Tel.:
+49 241 8089226; Fax: +49 241 8082484; E-mail: [email protected]
Abstract: We report a girl with opsoclonus-myoclonus syndrome related to
cerebral rubella infection that relapsed during adrenocorticotropin monotherapy
but stabilized with methotrexate add-on treatment. Methotrexate may be a new
therapeutic option in opsoclonus-myoclonus syndrome, reducing the need for
long-term high-dose adrenocorticotropin treatment and the risk of
steroid-related side effects.
