Plasmablastic lymphoma with an extra-oral location in a child with human immunodeficiency virus infection

Article type: Research Article

Authors: Panja, Satarupa Mukherjee | Panja, Buddhadev

Affiliations: Department of pediatrics, Medical College and Hospital, Kolkata, India | Department of pharmacology, MGM Medical College and LSK Hospital, Bihar, India

Note: [] Correspondence: Dr. Satarupa Mukherjee, 517, Brahmapur, Badamtala, Kolkata, 700096, India. Tel.: +91 9433722489; Fax: +91 3323509769; E-mail: [email protected]

Abstract: Plasmablastic lymphoma (PBL) is a rare type of non-Hodgkin lymphoma frequently related to HIV infection. We report a case of PBL in a 7 year old female child with transfusion-acquired HIV infection on antiretroviral therapy (ART). The presentation was a swelling in the skull and cervical lymphadenopathy. CT scan revealed bony erosions with meningeal enhancement. The patient was started on chemotherapy and cranial irradiation but succumbed to death in 5 months. This is the first reported case of PBL involving the skull and meninges in a HIV-infected child.

Keywords: HIV, Plasmablastic lymphoma, skull

DOI: 10.3233/JPI-140422

Journal: Journal of Pediatric Infectious Diseases, vol. 9, no. 2, pp. 119-121, 2014