Pediatric case of MRSA right-sided infective endocarditis with septic pulmonary embolism successfully treated by daptomycin in combination with gentamicin and rifampin

Article type: Research Article

Authors: Jalal, Zakaria | Camou, Fabrice | Roubertie, François | Iriart, Xavier | Thambo, Jean-Benoit

Affiliations: Department of Congenital Heart Diseases, Bordeaux University Hospital, Avenue Magellan, Pessac, France | Department of Internal Medicine and Infectious Diseases, Bordeaux University Hospital, Avenue Magellan, Pessac, France | Department of Cardiovascular Surgery, Bordeaux University Hospital, Avenue Magellan, Pessac, France

Note: [] Correspondence: Fabrice Camou, Service de Médecine Interne et Maladies Infectieuses, Hôpital Haut Lévêque, avenue de Magellan, 33604 Pessac Cedex, France. Tel.: +33 556795830; Fax: +33 556794771; E-mail: [email protected]

Abstract: We report a case of a 12 year old child with a ventricular septal defect (VSD) and right-sided MRSA endocarditis complicated by pulmonary septic emboli. The patients was treated successfully with daptomycin in combination with gentamicin and rifampin, followed by surgery to excise the vegetation and close the VSD.

Keywords: Endocarditis, daptomycin, MRSA, congenital heart disease

DOI: 10.3233/JPI-130391

Journal: Journal of Pediatric Infectious Diseases, vol. 8, no. 3, pp. 139-142, 2013