Affiliations: Department of Pediatrics, Division of Endocrinology,
Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand | Department of Medicine, University of Minnesota,
Minneapolis, MN, USA | Department of Pediatrics, Division of Infectious
Diseases, Faculty of Medicine, Chiang Mai University, Chiang Mai,
Thailand
Note: [] Correspondence: Dr. Peninnah Oberdorfer, M.D., PhD., Division
of Infectious Diseases, Department of Pediatrics, Faculty of Medicine, Chiang
Mai University, 50200, Chiang Mai, Thailand. Tel.: +66 53 946470; Fax: +66 53
946470; E-mail: [email protected]; or [email protected]
Abstract: We report a case of polycystic ovary syndrome in a 15-year-old human
immunodeficiency virus-infected female on highly active antiretroviral therapy
who developed hypertriglyceridemia, hyperinsulinemia due to insulin resistance,
and hyperandrogenism. Ultrasonography showed multiple small follicles at the
right ovary and lobulated follicles at the left ovary. Treatment of polycystic
ovary syndrome included insulin sensitizing agents (metformin, pioglitazone)
and a contraceptive for hyperandrogenism. We also encouraged life style
modification including regular exercise and dietary fat restriction. She
attained menarche 1 month after initiation of treatment.
