Pregnancy outcomes in two growth restricted fetuses with in utero cerebral lactate

Article type: Research Article

Authors: Andescavage, N.^{a; b} | Limperopoulos, C.^{b; c; d} | Evangelou, I.^{b; c; e} | Murnick, J.^{c; e} | du Plessis, A.^{b; d; *}

Affiliations: [a] Children’s National Medical Center, Division of Neonatology, Washington, DC, USA | [b] George Washington University School of Medicine and Health Sciences, Department of Pediatrics, Washington, DC, USA | [c] Children’s National Medical Center, Division of Diagnostic Imaging and Radiology, Washington, DC, USA | [d] Children’s National Medical Center, Division of Fetal-Transitional Medicine, Washington, DC, USA | [e] George Washington University School of Medicine and Health Sciences, Department of Radiology, Washington, DC, USA

Correspondence: [*] Corresponding author: Adre du Plessis, MBChB., Division of Fetal-Transitional Medicine, Children’s National Medical Center, 111 Michigan Avenue, N.W., 20010-2970 Washington, D.C, USA. Tel.: +1 202 476 3920; Fax: +1 202 476 3459; [email protected]

Abstract: Elevated cerebral lactate is increasingly detected by magnetic resonance spectroscopy in the human fetus diagnosed with various pathologic conditions. However, the significance of detectable cerebral lactate remains uncertain. We present two cases of fetal cerebral lactate with adverse pregnancy outcomes.

Keywords: Cerebral lactate, fetal growth restriction, fetal MRI, spectroscopy

DOI: 10.3233/NPM-15814084

Journal: Journal of Neonatal-Perinatal Medicine, vol. 8, no. 3, pp. 269-273, 2015