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Article type: Case Report
Authors: Phillips, J.a; * | Blask, A.b; c | DiPoto Brahmbhatt, A.d | Lawrence, A.c | Timofeev, J.e | Badillo, A.c; f | Andescavage, N.c; g
Affiliations: [a] Department of Obstetrics and Gynecology, George Washington University School of Medicine & Health Sciences, Washington, DC, USA | [b] Division of Diagnostic Imaging and Radiology, Children’s National Health System, Washington, DC, USA | [c] Fetal Medicine Institute, Children’s National Health System, Washington, DC, USA | [d] Division of Pathology and Laboratory Sciences, Children’s National Health System, Washington, DC, USA | [e] Department of Gynecology and Obstetrics, Division of Maternal Fetal Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA | [f] Department Division of Pediatric Surgery, Children’s National Health System, Washington, DC, USA | [g] Department of Neonatology, Children’s National Health System, Washington, DC, USA
Correspondence: [*] Address for correspondence: Jaclyn Phillips, Fetal Medicine Institute, Children’s National Health System, Washington, DC, USA. Tel.: +1 814 553 7021; E-mail: [email protected].
Abstract: Fetal lung interstitial tumor (FLIT) is a rare fetal malignancy that is typically diagnosed in the postnatal period, or, if recognized prenatally can mimic a benign lesion such as congenital pulmonary airway malformation. We present the earliest case of a FLIT tumor described by ultrasound and MRI at 26 weeks of gestation. Our case highlights features suggestive of FLIT including presentation later in gestation in combination with findings on fetal MRI such as a solid appearance with radiating curved bands of high signal within and along the periphery of the lesion (not as intensely high signal as the typical CPAM), possibly detailing a radiographic signature for these tumors. The role of betamethasone for these tumors is not known.
Keywords: Fetal lung interstitial tumor, congenital pulmonary airway malformation, immature mesenchymal interstitial tumor
DOI: 10.3233/NPM-180059
Journal: Journal of Neonatal-Perinatal Medicine, vol. 12, no. 4, pp. 473-477, 2019
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