Affiliations: [a] Department of Biomedical Engineering, Jordan University of Science and Technology, Irbid, Jordan
| [b] Department of Bioengineering, University of Illinois Urbana-Champaign, Urbana, IL, USA
| [c] Department of Rehabilitation Sciences, Jordan University of Science and Technology, Irbid, Jordan
| [d] Department of Biomedical Engineering, Rathinam Technical Campus, Coimbatore, India
Correspondence:
[*]
Corresponding author. Enas Abdulhay, Biomedical Engineering department, Jordan University of Science and Technology, 22110 Irbid, Jordan. Tel.: 0096227201000; E-mail: [email protected].
Note: [1] Equal contribution.
Abstract: Autism is a developmental disorder that influences social communication skills. It is currently diagnosed only by behavioral assessment. The assessment is susceptible to the experience of the examiner as well as to the descriptive scaling standard. This paper presents a computer aided approach to discrimination between neuro-typical and autistic children. A new method- based on the computing of the elliptic area of the Continuous Wavelet Transform complex plot of resting state EEG- is presented. First, the complex values of CWT, as a function of both time and frequency, are calculated for every EEG channel. Second, the CWT complex plot is obtained by plotting the real parts of the resulted CWT values versus the related imaginary components. Third, the 95% confidence value of the elliptic area of the complex plot is computed for every channel for both autistic and healthy subjects; and the obtained values are considered as the first set of features. Fourth, three additional features are computed for every channel: the average CWT, the maximum EEG amplitude, and the maximum real part of CWT. The classification of those features is realized through artificial neural network (ANN). The obtained accuracy, sensitivity and specificity values are: 95.9%, 96.7%, and 95.1% respectively.
