Effect of noise exposure (85 dB ) on testicular adrenocortical steroidogenic key enzymes, acid and alkaline phosphatase activities of sex organs in mature albino rats

Article type: Research Article

Authors: Ghosh, Debidas | Ghosh, Sampa | Chattopadhyay, Sandip | Debnath, Jogen

Affiliations: Department of Human Physiology with Community Health, Vidyasagar University, Midnapore-721 102, West Bengal, India

Abstract: Changes in the activities of &b.Delta;^5-3ß-hydroysteroid dehydrogenase (HSD) in testis and adrenal gland, 17ß-hydroxysteroid dehydrogenase in testis, acid and alkaline phosphatase in testis, prostate and seminal vesicle were observed in noise exposed mature rats at the intensity of 85 dB for 8 h/day for 45 days. The results indicated that noise exposed group showed a significant diminution in the activities of androgenic key enzymes &b.Delta;^5-3ß and 17ß-HSD, acid phosphatase in testis, prostate and seminal vesicle. There was a significant elevation in the activities of adrenal &b.Delta;^5-3ß-HSD, alkaline phosphatase in testis and other accessory sex organ in noise exposed group. Gonadosomatic, prostatosomatic and seminal vesiculo-somatic indexes were decreased significantly in noise exposed group. Therefore, it is evident that noise exposure at 85dB exerts a deleterious effect on testicular and adrenocortical activities.

Keywords: noise, hydroxysteroid dehydrogenase, acid phosphatase, alkaline phosphatase, sex organs, adrenal cortex

Journal: Journal of Environmental Sciences, vol. 12, no. 3, pp. 286-289, 2000