Affiliations: Department of Atomic and Molecular Physics, Manipal University, Manipal-576104, Karnataka, India
Correspondence:
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Corresponding author: A. Abdul Ajees, Department of Atomic and Molecular Physics, Manipal University, Manipal-576104, Karnataka, India. Tel.: +91 8147966458; E-mail:[email protected]
Abstract: The post-genomic era produces an overwhelming
amount of experimental data, but majority of such data lacks the
characterization of its functions. Structure based approaches are useful to
understand and characterize the functional aspects of proteins. Given the
burgeoning requirement of understanding the functional aspects of various
enzymes, we report a systematic structure based study of methyltransferases
bound with S-adenosyl-L-methionine (SAM). Through this work, we identified
the conserved amino acids of methyltransferase, which are interacting with
SAM.
Keywords: Amino acids, methyltransferase, protein data bank, S-adenosyl-L-methionine
