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Article type: Article Commentary
Authors: Volgman, Annabelle Santosa; * | Engelstein, Ericaa | Aggarwal, Neelum T.b
Affiliations: [a] Division of Cardiology, Rush University Medical Center, Chicago, IL, USA | [b] Department of Neurological Sciences, Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, IL, USA
Correspondence: [*] Correspondence to: Annabelle Santos Volgman, MD, FACC, FAHA, Rush Heart Center for Women, 1725 W. Harrison St., Suite 1159, Chicago, IL 60612, USA. E-mail: [email protected]; Twitter: @avolgman.
Abstract: In a recent issue of the Journal of Alzheimer’s Disease, Zinman et al. investigated the role of sex in the risk of cognitive impairment in 5,969 patients with a stroke or transient ischemic attacks. Using a short validated clinical screening tool, they noted that men had a 34% higher risk of screening positive for post-stroke cognitive impairment after adjusting for age, education, and stroke severity compared to women. This study highlights that more large, prospective, and multicenter studies are needed to evaluate sex-specific changes after a stroke since sex differences exist in many aspects of stroke presentation and management.
Keywords: Alzheimer’s disease, cognitive impairment, post-stroke cognitive impairment, sex differences, strokes
DOI: 10.3233/JAD-230520
Journal: Journal of Alzheimer's Disease, vol. 95, no. 2, pp. 407-409, 2023
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