An Exploration of the Own-Age Effect on Facial Emotion Recognition in Normal Elderly People and Individuals with the Preclinical and Demented Alzheimer’s Disease

Article type: Research Article

Authors: Chuang, Yu-Chen^a | Chiu, Ming-Jang^{b; c; d} | Chen, Ta-Fu^b | Chang, Yu-Ling^{a; b; f} | Lai, Ya-Mei^b | Cheng, Ting-Wen^{b; c} | Hua, Mau-Sun^{a; b; e; *}

Affiliations: [a] Department of Psychology, College of Science, National Taiwan University, Taiwan | [b] Department of Neurology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan | [c] Graduate Institute of Brain and Mind Sciences, College of Medicine, National Taiwan University, Taiwan | [d] Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taiwan | [e] Department of Psychology, Asia University, Taichung, Taiwan | [f] Neurobiology and Cognitive Science Center, National Taiwan University, Taipei, Taiwan

Correspondence: [*] Correspondence to: Mau-Sun Hua, Department of Psychology, College of Science, National Taiwan University, Taiwan. Tel.: +886 2 3366 3101; E-mail: [email protected].

Abstract: Background:The issue of whether there exists an own-effect on facial recognition in the elderly remains equivocal. Moreover, currently the literature of this issue in pathological aging is little. Objective:Our study was thus to explore the issue in both of healthy older people and patients with AD Methods:In study 1, 27 older and 31 younger healthy adults were recruited; in study 2, 27 healthy older adults and 80 patients (including subjective cognitive decline (SCD), mild cognitive impairment (MCI), and Alzheimer’s disease (AD) groups) were recruited. Participants received the Taiwan Facial Emotion Recognition Task (FER Task), and a clinical neuropsychological assessment. Results:No significant differences on the FER test were found among our groups, except for sadness recognition in which our MCI and AD patients’ scores were remarkably lower than their healthy counterparts. The own-age effect was not significantly evident in healthy younger and older adults, except for recognizing neutral photos. Our patients with MCI and AD tended to have the effect, particularly for the sad recognition in which the effect was significantly evident in terms of error features (mislabeling it as anger in younger-face and neutral in older-face photos). Conclusion:Our results displayed no remarkable own-age effect on facial emotional recognition in the healthy elderly (including SCD). However, it did not appear the case for MCI and AD patients, especially their recognizing those sadness items, suggesting that an inclusion of the FER task particularly involving those items of low-intensity emotion in clinical neuropsychological assessment might be contributory to the early detection of AD-related pathological individuals.

Keywords: Alzheimer’s disease, amnestic mild cognitive impairment, early detection, facial emotion recognition task, subjective memory decline, Taiwanese

DOI: 10.3233/JAD-200916

Journal: Journal of Alzheimer's Disease, vol. 80, no. 1, pp. 259-269, 2021