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Issue title: Alzheimer's Disease: Detection, Prevention, and Preclinical Treatment
Guest editors: Jack C. de la Torre
Article type: Review Article
Authors: Polidori, Maria Cristina; *
Affiliations: Geriatrics Department, University of Cologne, Medical Faculty, Cologne, Germany
Correspondence: [*] Correspondence to: Prof. M.C. Polidori, MD, PhD, FRCP, Geriatrics Department, University of Cologne, Medical Faculty, Cologne, Germany. E-mail: [email protected].
Abstract: Malnutrition-, obesity-, and Alzheimer's disease (AD)-related burden to patients and society are among the main public health challenges of our time in both developed and developing countries. Poor nutrition as part of an unhealthy lifestyle is one of the modifiable risk factors for AD, and its improvement has been the recent focus of several interventional and epidemiologic studies. There is an impressive body of evidence supporting the beneficial role of balanced nutrition in lowering the risk of dementia, but despite worldwide dementia epidemics, lack of information still leads to (too) late diagnosis and (symptomatic) interventions. The aim of this work is to critically summarize knowledge on the preventive effects of natural nutrition against AD onset and to present a multidimensional and individualized approach aimed at delaying AD onset in community dwellers with subjective and mild cognitive complaints.
Keywords: Alzheimer's disease, antioxidant, clinical trial, counseling, mild cognitive impairment, natural nutrition, oxidative stress
DOI: 10.3233/JAD-141539
Journal: Journal of Alzheimer's Disease, vol. 42, no. s4, pp. S475-S482, 2014
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