A Phenotype of Atypical Apraxia of Speech in a Family Carrying SQSTM1 Mutation

Article type: Research Article

Authors: Boutoleau-Bretonnière, Claire^{a; b; c; *} | Camuzat, Agnès^{d; e; f} | Le Ber, Isabelle^{d; e; f; g; h} | Bouya-Ahmed, Kawtar^{d; e; f} | Guerreiro, Ritaⁱ | Deruet, Anne-Laure^{a; b} | Evrard, Christelle^{a; b} | Bras, Joséⁱ | Lamy, Estelle^{a; b} | Auffray-Calvier, Elisabeth^j | Pallardy, Amandine^k | Hardy, Johnⁱ | Brice, Alexis^{d; e; f} | Derkinderen, Pascal^{a; b; l} | Vercelletto, Martine^{a; b}

Affiliations: [a] CHU Nantes, Centre de Mémoire et de Ressource et Recherche (CM2R), Nantes, France | [b] Inserm, CIC 04, Nantes, France | [c] Laboratoire d'études des mécanismes cognitifs, EA 3082, Université Lyon 2, Bron F-69500, France | [d] Inserm, UMR_S1127, CRICM, F-75013, Paris, France | [e] UPMC Univ Paris 06, UMR_S975, F-75013, Paris, France | [f] CNRS UMR 7225, F-75013, Paris, France | [g] AP-HP, Hôpital de la Pitié-Salpêtrière, Centre de Référence des Démences Rares, F-75013, Paris, France | [h] AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Neurologie, F-75013, Paris, France | [i] Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK | [j] Service de Neuroradiologie, CHU de Nantes, Nantes, France | [k] Service de Médecine Nucléaire, CHU de Nantes, Nantes, France | [l] Inserm, UMR 913, Nantes, France

Correspondence: [*] Correspondence to: Claire Boutoleau-Bretonnière, Centre Mémoire Recherche et Ressources (CMRR), Clinique Neurologique CHU Nord, 44093 Nantes, France. Tel.: +33 240 165 422; Fax: +33 240 165 397; E-mail: [email protected].

Keywords: Amyotrophic lateral sclerosis, apraxia of speech, behavioral variant of FTD, frontotemporal lobar degeneration, non fluent variant of primary progressive aphasia, p62, Paget disease of bone, progressive non-fluent aphasia, progressive supranuclear palsy, SQSTM1

DOI: 10.3233/JAD-141512

Journal: Journal of Alzheimer's Disease, vol. 43, no. 2, pp. 625-630, 2015