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Article type: Review Article
Authors: Koppel, Jeremy; * | Davies, Peter
Affiliations: The Albert Einstein College of Medicine and The Litwin-Zucker Research Center for the Study of Alzheimer's Disease and Memory Disorders, The Feinstein Institute for Medical Research, Manhasset, NY, USA
Correspondence: [*] Corresponding author: Jeremy Koppel MD, The Litwin-Zucker Research Center for the Study of Alzheimer's Disease and Memory Disorders, The Feinstein Institute for Medical Research, Manhasset, NY 11030, USA. E-mail: [email protected].
Abstract: The endocannabinoid system is rapidly emerging as a potential drug target for a variety of immune-mediated central nervous system diseases. There is a growing body of evidence suggesting that endocannabinoid interventions may have particular relevance to Alzheimer's disease. Here we present a review of endocannabinoid physiology, the evidence that underscores its utility as a potential target for intervention in Alzheimer's disease, and suggest future pathways of research.
Keywords: Alzheimer's disease, CB1, CB2, dementia, endocannabinoids
DOI: 10.3233/JAD-2008-15315
Journal: Journal of Alzheimer's Disease, vol. 15, no. 3, pp. 495-504, 2008
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