Affiliations: [a] Laboratory of Physiology and Biokinetic – UNIG Campus
V, Itaperuna, RJ, Brazil | [b] Department of Biological Sciences, Universidade
Estadual do Sudoeste da Bahia (UESB), Jequié, Bahia, Brazil | [c] Department of Biomedical Engineering, Universidade
Camilo Castelo Branco, São Paulo, Brazil | [d] Laboratory of Human Movement Studies, University
Foundation of Itaperuna (FUNITA, Itaperuna, RJ, Brazil
Note: [] Address for correspondence: Marco Machado, Laboratory of Human
Movement Studies, Universitary Foundation of Itaperuna (FUNITA), R Silva
Jardim, 775, Aeroporto, Itaperuna, RJ, Brazil CEP 28.300-000. Tel.: +55 22 3824
4040; Fax: +55 22 3824 4040; E-mail: [email protected]
Abstract: The aim of this study was to assess how much risk a resistance
exercise can provide to individuals who have distinguished hyperCKemia
response. Twenty-three healthy men performed an exercise protocol, during which
4 sets of biceps curl were performed at 85% of 1 repetition maximum (1RM). Each bout was performed to voluntary
fatigue and the workout volume completed was calculated. Subjects provided
blood samples prior, and at 24, and 48 h following exercise to evaluate serum
creatine kinase (CK) activity. Based on serum CK activity responses the
subjects were separated into two groups called: Normal Responders (NR) or High
Responders (HR). A great interindividual variability in serum CK activity
following exercise and a significant difference between NR and HR were
observed. The workout volume demonstrated a significant reduction along sets
but without difference between NR and HR. Our main finding was the great
inter-individual variability in serum CK activity that is seen even when using
a single exercise performed on a the day-to-day basis.
