Affiliations: Department of Ophthalmology, Otorhinolaringology and
Head and Neck Surgery, School of Medicine of Ribeirão Preto, University
of São Paulo, Ribeirão Preto, SP, Brazil | Department Medical Clinical, School of Medicine of
Ribeirão Preto, University of São Paulo, Ribeirão Preto,
SP, Brazil | Department of General and Specialized Nursing, Nursing
School of Ribeirão Preto, University of São Paulo,
Ribeirão Preto, SP, Brazil
Note: [] Corresponding author: Ana Paula M. Fernandes, Department of
General and Specialized Nursing, School of Nursing of Ribeirão Preto,
University of São Paulo, 3900 Av. Bandeirantes, Monte Alegre, 14
049-902, Ribeirão Preto, SP, Brazil. Tel.: +55 16 3602 3414; Fax: +55 16
3633 3271; E-mail: [email protected]
Abstract: Background/aims: The frequency of HLA markers associated with rapid
progression to AIDS was evaluated in Brazilian patients with AIDS exhibiting or
not toxoplasmic retinochoroiditis (TRC). Methods: 98 AIDS patients (25 with TRC, 43 with anti-T. gondii
antibodies but without TCR, and 30 without anti-T. gondii antibodies and
without TCR) were studied. Results: The HLA-B35 was significantly increased in TRC group
(p=0.0038). Conclusion: The presence of HLA-B35 may simultaneously predispose to
progression to AIDS and TRC.
