Development tracks for cancer prevention markers

Issue title: CANCER BIOMARKERS

Article type: Research Article

Authors: Baker, Stuart G. | Kramer, Barnett S. | Prorok, Philip C.

Affiliations: Biometry Research Group, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA | Office of Disease Prevention, National Institutes of Health, Bethesda, MD, USA

Note: [] Corresponding author: Stuart G. Baker, Sc.D. National Cancer Institute, EPN 3131, 6130, Executive Blvd MSC 7354, Bethesda, MD 20892-7354, USA. Fax: +1 301 402 0816; E-mail: [email protected]; URL: http://www.cancer.gov/prevention/bb/baker.html

Abstract: We provide a general framework for describing various roles for biomarkers in cancer prevention research (early detection, surrogate endpoint, and cohort identification for primary prevention) and the phases in their evaluation.

Journal: Disease Markers, vol. 20, no. 2, pp. 97-102, 2004